Research
Current Research being carried out within the Centre:
Oncology
- Studying the impact of doctor's awareness of patients' assessment of their quality of life on patients' functional behaviour: a randomised double-blind, controlled study - Velindre Hospital, Cardiff
- Study the impact of communicating medical information on patients' quality of life - Velindre Hospital, Cardiff
- Development of the Cardiff Short Form MQoL Questionnaire - Velindre Hospital, Cardiff
Dementia
- Psychometric evaluation of the Community Dementia Quality of Life Profile (CDQLP) - Llandough Hospital, Cardiff & Gwent
- Development of the electronic version of the CDQLP
- Development of a patient/carer dementia-specific quality of life instrument.
Renal
- Psychometric evaluation of the Renal Quality of Life Profile (RQLP) in pre-dialysis patients
- Study of patient compliance in kidney failure
- Development of a Renal Quality of Life Profile [RQLP] (conceptualisation, design, content validation, practicality, acceptability/applicability, validity, sensitivity/responsiveness)
- End stage renal disease: measuring outcome and need
Parkinson's Disease
- Comparison of generic and disease-specific quality of life instruments - a UK multicentre study
- Drug profiling and assessment of quality of life in Parkinson's disease patients
- A study to assess knowledge of medications in people with Parkinson's disease
- Study of the quality of life in chronic progressive neurological disease
- The influence of treatment complications on patient reported outcomes in Parkinson's disease
- Development of the Welsh Movement Disorder eNetwork
- Benefit-risk assessment of medicines and the development of a new model using multi - criteria decision analysis (MCDA)
- Evaluation and clinical application of health-related quality of life in Parkinson's disease
- Prevalence of drug treatments for depression and dementia in Parkinson's disease patients
- Development of an electronic decision aid for Parkinson's disease using MCDA
- Measurement of the impact of different services on quality of life of patients with Parkinson's Disease
- Development of a Parkinson's Disease Drug Information Helpline for patients and carers
- Development of the a Parkinson's Disease Welsh National Registry
- Development of Parkinson's Disease-specific health-related quality of life instruments
Pharmacoepidemiology
- The evaluation of models for measuring the benefit/risk ration of pharmaceutical products as a tool for the assessment of new product and the re-assessment of marketed products
- Evaluation of the summary of product characteristics and the product circulars reflection of serious adverse events pre-and postmarketing
- Case control study of depression and its treatment in Parkinson's Disease using the General Practice Morbidity Database (GPMD)
- Translating the science of health measurement into practice
- Medication-related problems of cardiovascular drugs and its socioeconomic impacts
- Development of a comprehensive "Compendium of Quality of Life Instruments"
Pharmaceutical Regulatory Issues
- Evaluation of changes in the regulatory environment that have had a major impact on drug development in recent years
- Development of models for improving efficiency and productivity in pharmaceutical R & D
- A study of the approval system for pharmaceutical products in Saudi Arabia - a comparison with other countries in the region, Europe, Australia and the United States
- Review process for marketing pharmaceutical products in the Gulf States and its impact on patients' access to medicines
- Evaluation of quality measures applied to the regulatory review process of major regulatory authorities
- Efficiency and productivity of the International pharmaceutical industry and its sustainability in the 21st Century
Community Pharmacy
- Health-related quality of life assessment by community pharmacists - its relevance and practicality as an outcome measure in providing pharmaceutical care.
- A multi-national project studying the cross-cultural differences in perceptions of the role of the community pharmacist as a health care provider-community pharmacist's and general practitioner's perspective
- Development and application of validation methods for community pharmacy-confirming the effectiveness of the pharmacist in a community setting
Pharmacoeconomic
- To study the socioeconomic impact of HAART protease inhibitor for initial HIV1 treatment given total healthcare associated with its management and determine the most cost effective treatment
Patient Reported Outcomes and Compliance - Adherence
- Study of patient compliance and physician behaviour
- Assessment of quality of life in home haemodialysis and CAPD patients and evaluation of patient/carer compliance
