Welsh School of Pharmacy

Qualifications

• PhD in synthetic organic chemistry, University of Leeds (1990-1993)
• BSc (Hons) Chemistry, University of Leeds (1987-1990)

Research Interests

I am a medicinal chemist with extensive experience of the synthesis and biological evaluation of new small molecules with potential antitumour activity. My research interests can be divided into the following categories:

• Breast cancer drug design and discovery
• Selective apoptosis induction in cancer cells
• Protein-protein interactions as cancer drug targets
• E3 ubiquitin ligases as therapeutic targets in cancer
• Diagnostic imaging (Positron Emission Tomography) in oncology and neuroscience
• Characterisation of novel psychoactive substances, in conjunction with Public Heath Wales and Llandough Hospital Cardiff

Coordinator of the School's Medicinal Chemistry Research Discipline

Teaching Profile

Undergraduate

• Module leader (PH3202) and Senior Lecturer on MPharm degree
• PH1123 Structure and Function of Cells and Microbes (lectures on DNA and RNA)
• PH1125 Chemical and Biological Properties of Drug Molecules (lectures/workshops and laboratory classes on physical properties of drug molecules and enzyme inhibitors)
• PH2106 Introduction to Drug Design and Synthesis (lectures on enzyme inhibitors and prodrugs)
• PH3101 Optimisation of Drug Design (lectures on cancer therapeutics and tropical medicine)
• PH3202 Research Methodology (paper appraisal and research methods)
• PH4105 Problem Solving in Pharmaceutical Sciences (integrated pharmaceutical sciences workshops)
• PH4208 Pharmacy Research Project (supervision of undergraduate final year projects)

External Examiner

• University College London, School of Pharmacy