Welcome to the World of Nanomedicines
Bioresponsive Polymer Therapeutics: Synthesis and Characterisation of Novel Nanomedicines

EPSRC Platform Grant 2006 – 2010


Attendees at one of the regular scientific sandpit meetings

Recent Publications

Many of the groups webpages contain lists of published work, but here we highlight some of the more Platform related publications.

    Dextrin-rhEGF conjugates as bioresponsive nanomedicines for wound repair Joseph Hardwicke, Elaine L. Ferguson, Ryan Moseley, Phil Stephens, David W. Thomas, and Ruth Duncan J. Controlled Rel. 130(3), 275-283, 2008
    The use of fluorescence microscopy to define polymer localisation to the late endocytic compartments in cells that are targets for drug delivery Richardson SCW, Wallom KL, Ferguson EL, Deacon SPE, Davies MW, Powell AJ, Piper RC, Duncan R J. Controlled Rel. 127(1), 1-11, 2007
    Studies of the Mechanism of Interaction of a Bioresponsive Endosomolytic Polyamidoamine with Interfaces. 1 Micelles as Model Surfaces Peter C. Griffiths, Zeena Khayat, Stephanie Tse, Richard K. Heenan, Stephen M. King and Ruth Duncan Biomacromolecules 8, 1004-1012, 2007
    Physicochemical characterization of thermoresponsive poly(N-isopropylacrylamide)-poly(ethylene imine) coploymers Peter C. Griffiths, Cameron Alexander, Renuka Nilmini, Sivanand S. Pennadam, Stephen M. King and Richard Heenan Biomacromolecules, 9(4), 1170-1178, 2008
    Polymer Therapeutics Designed for a Combination Therapy of Hormone-Dependent Cancer Vicent M.J., Greco F., Nicholson R.I., Paul A., Griffiths P.C. and Duncan R. Angewandte Chemie International Edition 44, 2-6, 2005
    Polymer-drug conjugates: Current Status and Future Trends Frontiers in Biomedical Science Francesca Greco and María J. Vicent Frontiers in Bioscience 13, 2744-56, 2008
    Probing the Solution Conformation of HPMA-Doxorubicin Conjugates with Small-angle Neutron Scattering. Alison Paul, María J. Vicent, Ruth Duncan. Biomacromolecules 8(5) 1573-1579, 2007.
    A small-angle neutron scattering and rheology study of the composite of chitosan and gelatinY. Wang, D. Qiu, T. Cosgrove, M.L. Denbow, , Colloids and Surfaces B: Biointerfaces (2008) in press
    A comparison of the effect of chitosan and chitosan-coated vesicles on monolayer integrity and permeability across Caco-2 and 16HBE14o-cells Kudsiova, L and Lawrence, MJ JOURNAL OF PHARMACEUTICAL SCIENCES 97(9), 3998-4010, 2008
    Characterisation of chitosan-coated vesicles encapsulating DNA suitable for gene delivery Kudsiova, L, Arafiena, C and Lawrence, MJ JOURNAL OF PHARMACEUTICAL SCIENCES 97(9), 3981-3997, 2008
    Small-angle neutron-scattering studies of the microemulsion component of an aqueous nanosuspomicroemulsion Al-Olbaidi, H; Jaiyesimi, O; Lawrence, MJ JOURNAL OF PHARMACY AND PHARMACOLOGY 60, A24-A24, 2008