 |
Search all files of this site |
|
|
|
|
Proteases are listed according to their celluar
localisation and in alphabetical order. MWs of periplasmic and outer
membrane proteases are given for the unprocessed precursor proteins.
Clicking on the protein name will open the latest SwissProt
file.
Proteases localised in the
Cytoplasm
Cytoplasmic
membrane
Periplasm
Outer membrane
Cytoplasm
ATP-dependent Clp protease proteolytic
subunit
(clpP
)
| Peptidase family | S14 InterPro
|
| Function | Heat shock protein,
chymotrypsin-like activity, major role in the degradation of misfolded
proteins
| | Structure |  PDB
|
| MW | 23186
Da
207
aa
|
Lon protease homolog
(ycbZ
)
| Peptidase family | S16
| | Function | Lacks ATP ase domain of Lon
| | Structure |
| | MW | 65818 Da
586
aa
|
Protease Lon
(lon
)
| Peptidase family | S16 InterPro
|
| Function | Heat shock protein,
ATP-dependent Ser protease, broad substrate specificity
| | Structure |
| | MW | 87438 Da
784
aa
|
Alpha-aspartyl dipeptidase /Peptidase
E
(pepE
)
| Peptidase family | Serine (according to MEROPS)
| | Function | Hydrolyses dipeptides
containing n-terminal aspartate residues
| | Structure |
| | MW | 24570 Da
229
aa
|
Protease II
(ptrB
)
| Peptidase family | S9A InterPro
|
| Function | Cleaves after Lys and Arg
residues
| | Structure |
| | MW | 79490 Da
686 aa
|
Cytoplasmic
membrane
Protease DegS
(degS
)
| Peptidase family | S2C InterPro
|
| Function | Essential serine
protease, Cleaves RseA to induce sigma E cascade
| | Structure |  PDB
| | MW | 37581 Da
355 aa
|
GlpG
(glpG
)
| Peptidase family | S54 InterPro
|
| Function |
| | Structure | transmembrane domains: 6 (potential)
| | MW | 31307 Da
276 aa
|
Leader peptidase I
(LepB
)
| Peptidase family | S26 InterPro
|
| Function | General leader
peptidase
| | Structure |  PDB
2 TM, periplasmic N-and C-termini
| | MW | 35960 Da
324
aa
|
Possible Ser protease SohB
(sohB
)
| Peptidase family | S49 InterPro
|
| Function | Suppressor of degP(htrA)
null mutation
| | Structure | 1 TM?
| | MW | 39366 Da
349 aa
|
Signal peptide
peptidase/Protease IV
(sppA
)
| Peptidase family | S49 InterPro
|
| Function | Degrades cleaved signal
peptides
| | Structure | 3 TM?
| | MW | 67233 Da
618 aa
|
Periplasm
PBP-5, D-alanyl-D-alanine carboxypeptidase fraction A
(dacA
)
| Peptidase family | S11InterPro
|
| Function | Cell wall formation
| | Structure |
| | MW | 44444 Da
403 aa (1-29 signal
pept.)
|
PBP-4, D-alanyl-D-alanine carboxypeptidase
(dacB
)
| Peptidase family | S13InterPro
|
| Function | Cell wall formation
| | Structure |
| | MW | 51798 Da
477 aa (1-20 signal
pept.)
|
PBP-6, D-alanyl-D-alanine carboxypeptidase fraction C
(dacC
)
| Peptidase family | S11InterPro
|
| Function | Cell wall formation
| | Structure |
| | MW | 43609 Da
400 aa (1-27 signal
pept.)
|
PBP-6B, D-alanyl-D-alanine carboxypeptidase
(dacD
)
| Peptidase family | S11InterPro
|
| Function | Cell wall formation
| | Structure |
| | MW | 43346 Da
388 aa (1-21 signal
pept.)
|
Protease Do
(degP/htrA
)
| Peptidase family | S2C InterPro
|
| Function | Heat shock protein,
serine protease and chaperone ectivities, required at high temperature,
virulence factor, involved in refolding and degradation of damaged
proteins
| | Structure |  PDB
| | MW | 49439 Da
474 aa (1-26 signal
pept.)
|
Protease DegQ
(degQ
)
| Peptidase family | S2C InterPro
|
| Function | Serine
protease
| | Structure | 2 PDZ domains
| | MW | 47205 Da
455 aa (1-27 signal
pept.)
|
PBP-7, D-alanyl-D-alanine-endopeptidase
(pbpG or b2134
)
| Peptidase family | S11InterPro
|
| Function | Cell wall formation
| | Structure |
| | MW | 34245 Da
313 aa (1-28 signal
pept.)
|
Tail-specific protease Prc/Tsp
(tsp
)
| Peptidase family | S41 InterPro
|
| Function | Degrades proteins
containing a 11 residue C-term. ssrA degradation tag
| | Structure | 1 PDZ
domain
| | MW | 76663 Da
682 aa (1-22 signal
pept.)
|
UmuD
(umuD
)
| Peptidase family | S24 InterPro
|
| Function |
| | Structure |
| | MW | 15063 Da
139 aa (1-24 signal
pept.)
|
Putative protease YdgD
(ydgD
)
| Peptidase family | S2B InterPro
|
| Function |
| | Structure |
| | MW | 29277 Da
273 aa (1-21 signal
pept.)
|
Outer membrane
OmpT/ProteaseVII
(ompT
)
| Peptidase family | S18 InterPro
|
| Function | The 3D structure questions that OmpT is a ser protease.
| | Structure |  PDB
| | MW | 35562 Da
317 aa (1-20 Signal
peptide)
|
|
|
Serine Proteases of E.
coli
