20 - 30 kDa

Hypothetical 20.0 kD protein in agaI-mtr intergenic region precursor (yraP )

function
interaction
regulation
MW					20028 Da; 191 aa

17.3 kD protein in murA-rpoN intergenic region precursor (yhbN )

function
interaction
regulation
MW					20127 Da; 185 aa

18.2 kD protein in cysQ-msrA intergenic region precursor (ytfJ )

function
interaction
regulation
MW					20420 Da; 184 aa

Peptidyl-prolyl cis-trans isomerase A precursor (ppiA )

function					accelerate the folding of proteins
interaction
cofactors
regulation					inhibition by cyclosporin A
					3d-structure
MW					20431 Da; 190 aa

Vitamin B12 transport protein precursor (btuE )

function					not essential for B12 transport, but auxiliary component of the transport system
interaction
regulation
MW					20469 Da; 183 aa

Cytochrome c-type protein NrfB precursor (nrfB )

function					terminal reductase of the formate-dependent pathway for nitrite reduction to ammonia
interaction					binds five heme groups per molecule
regulation
MW					20714 Da; 188 aa

PapJ protein precursor (papJ )

function					maintains pilus integrity, may function as chaperone in the correct assembly of PapA subunits
interaction
regulation
MW					20729 Da; 193 aa

Thiol:disulfide interchange protein DsbE precursor (ccmG )

function					disulfide bond formation, also acts as disulfide oxidoreductase in cytochrome c biogenensis
interaction
cofactors
regulation
MW					20809 Da; 185 aa

PrsJ protein precursor (prsJ )

function					maintains pilus integrity, may function as chaperone in the correct assembly of PapA
interaction
regulation
MW					20836 Da; 193 aa

18,7 kD protein in htrB-dinI intergenic region precursor (yceI )

function
interaction
regulation
MW					20912 Da; 191 aa

Osmotically inducable protein Y precursor (osmY )

function
interaction
regulation					induced at high osmolariry
MW					21074 Da; 201 aa

Outer membrane lipoproteins carrier precursor (lolA )

function					translocates lipoproteins from IM to OM
interaction					forms complex with lipoprotein
regulation
MW					22628 Da; 204 aa

Thiol:disulfide interchange protein DsbA precursor (dsbA )

function					disulfide bond formation in e.g. PhoA, OmpA, pilus biogenesis
interaction					reoxidised by DsbB
cofactors
regulation
					3d-structure
MW					23104 Da; 208 aa

Flagella Basal Body P-Ring Formation Protein FlgA precursor (flgA )

function					involved in assembly process of p-ring formation
interaction					probably with FlgF
regulation
MW					23519 Da; 219 aa

Acyl-CoA thioesterase I precursor (tesA )

function					hydrolyzes only long chain (C12-C18) acyl thioesters Catalytic activity: 2-lysophosphatidiylcholine + H2O = glycerophosphocholine + a fatty acid anion
interaction
cofactors
regulation
					monomer
MW					23622 Da; 516 aa

Hypothetical ABC transporter binding protein Yrbc precursor (yrbC )

function					probably part of a binding-protein-dependent transport system involved in toluene tolerance
interaction
regulation
MW					23962 Da; 211 aa

Chaperone protein FocC precursor (focC )

function					involved in biogenesis of F1C fimbriae
interaction
regulation
MW					25199 Da; 227 aa

Hypothetical 25.3 kD fimbrial chaperone in gltF-nanT intergenic region precursor
(yhcA )

function
interaction
regulation
MW					25339 Da; 224 aa

Hypothetical 25.4 kD fimbrial chaperone in pepN-pyrD intergenic region precursor (ycbR )

function					could be required for the biogenesis of the putative YcbQ fimbria
interaction
regulation
MW					25388 Da; 233 aa

Chaperone protein SfmC precursor (sfmC )

function					required for the biogenesis of SfmA Fimbriae
interaction					binds and interacts with SfmH
regulation
MW					25457 Da; 230 aa

Thiol:disulfide interchange Protein DsbC precursor (dsbC )

function					disulfide bond formation, also acts as disulfide isomerase
interaction					reoxidised by DsbD
cofactors
regulation
					homodimer
MW					25622 Da; 236 aa

Hypothetical 25.7 kD fimbrial chaperone in agaI-mtr intergenic region precursor (yraI )

function					could be required for the biogenesis of the putative YraH fimbria
interaction
regulation
MW					25676 Da; 231 aa

Class B acid phosphatase precursor (aphA )

function					Broad spectrum dephosphorylating enzyme
interaction
cofactors
regulation					Activated by Mg2+ and ethanol; inhibited by EDTA, nucleosides, inorganic phosphate and Ca2+
					homotetramer
MW					26103 Da; 237 aa

Hypothetical 26.6 kD fimbrial chaperone in gatY-mrp intergenic region precursor
(yehC )

function
interaction
regulation
MW					26589 Da; 239 aa

Hypothetical protein YggE
(yggE )

function
interaction
regulation
MW					26635 Da; 246 aa

Chaperone protein FimC precursor (fimC )

function					required for the biogenesis of type 1 fimbriae
interaction					binds and interacts with FimH
regulation
					3d-structure
MW					26689 Da; 241 aa

Endonuclease I (endA )

function					Endonucleolytic cleavage to 5'-phosphodinucleotide and 5'-phosphooligonucleotides
interaction
regulation
					3d-structure
MW					26709 Da; 2351 aa

Chaperone protein PapD precursor (papD )

function					mediates assembly of P pili
interaction					forms soluble multimeric complexes with pili subunits
regulation
					3d-structure
MW					26803 Da; 239 aa

Chaperone protein CssC precursor (CSC1) (cssC )

function					involved in the biogenesis of the CS6 fimbria
interaction
regulation
MW					26832 Da; 232 aa

Chaperone protein CssC precursor (CSC2) (cssC )

function					involved in the biogenesis of the CS6 fimbria
interaction
regulation
MW					26716 Da; 232 aa

Arginine-binding protein 2 precursor (artJ )

function					binds arginine
interaction
regulation
MW					26829 Da; 243 aa

Chaperone protein Cs31 precursor (CS31)  

function					essential for biogenesis of mature cs3 pili
interaction
regulation
MW					26908 Da; 241 aa

Arginine-binding protein 1 precursor (artI )

function					binds arginine
interaction
regulation
MW					26929 Da; 243 aa

Hypothetical fimbrial chaperone in nei-gltA intergenic region precursor (ybgP )

function					could be required for the biogenesis of the putative YbgD fimbria
interaction
regulation
MW					26954 Da; 242 aa

Hypothetical fimbrial chaperone in pepN-pyrD intergenic region precursor (ycbF )

function
interaction
regulation
MW					26982 Da; 245 aa

Chaperone protein NfaE precursor (nfaE )

function					involved in the biogenensis of Nfa-I adhesin
interaction
regulation
MW					27048 Da; 247 aa

Chaperone protein EcpD precursor (ecpD )

function					probably mediates assembly of a pilin
interaction
regulation					induction by heat shock
MW					27054 Da; 246 aa

Glutamine-binding protein precursor (glnH )

function					involved in Gln -transport
interaction
regulation					induction: lack of glutamin
					3d-structure
MW					27190 Da; 248 aa

Molybdate-binding protein precursor (modA )

function					binds molybdate with high specificity and affinity
interaction
regulation
MW					27364 Da; 257 aa

Thiol:disulfide interchange protein DsbG precursor (dsbG )

function					involved in disulfide bond formation
interaction
cofactors
regulation
MW					27495 Da; 248 aa

Hypothetical fimbrial chaperone in aroC-fadL intergenic region precursor (yfcS )

function
interaction
regulation
MW					27728 Da; 250 aa

Lysine-arginine-ornithine-binding protein precursor (argT)

function
interaction					ArgT and HisJ interact with HisP
regulation
MW					27991 Da; 260 aa

Histidine-binding protein HBP precursor (hisJ )

function					component of high-affinity histidine permease
interaction
regulation
					3d-structure
MW					28483 Da; 260 aa

Hypothetical fimbrial chaperone in ribB-glgS intergenic region precursor (yqiH )

function
interaction
regulation
MW					28864 Da; 252 aa

FkbP-type peptidyl-prolyl cis-trans isomerase FkpA precursor (fkpA )

function					folding of extracytoplasmic proteins
interaction
cofactors
regulation
MW					28882 Da; 270 aa

FliY protein precursor (fliY )

function					Cystin binding protein
interaction
regulation					sulfate starvation induced
MW					29039 Da; 266 aa

Chaperone Protein ClpE precursor (clpE )

function					involved in the biogenesis of cs31 capsule-like antigen
interaction
regulation
					immunglobulin fold
MW					29041 Da; 263 aa

BtuF protein precursor (btuF )

function					Vitamin B12 binding protein
interaction
regulation
MW					29367 Da; 266 aa

Ribonuclease Iprecursor (rna )

function					Cleaves the phosphodiester bond between any two nucleotides. Preference for cytidylic or guanylic acid.
interaction					two isoforms encoded by same gene
cofactors
regulation
					four disulfide bonds
MW					29617 Da; 268 aa

30 - 40 kDa

Penicillin-insensitive murein endopeptidase precursor (mepA )

function					murein removal from the sacculus, may faciliate integration of nascent murein strands into sacculus
interaction					penicillin insensitive
cofactors
regulation
MW					30136 Da; 274 aa

D-ribose-binding protein precursor (rbsB )

function					high affinity D-ribose transport, primary chemoreceptor for chemotaxis
interaction
regulation
					3d-structure
MW					30950 Da; 296 aa

Probable N-acetylmuramoyl-L-alanine amidase YbjR (ybjR )

function					Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides
interaction
regulation
MW					31072 Da; 276 aa

Maltose operon protein precursor (malM )

function					not yet known
interaction
regulation					MalT-dependent
MW					31943 Da; 306 aa

Potential choline binding protein (yehz )

function
interaction
regulation
MW					32609 Da; 305 aa

Potential YeiE protein (yeiE )

function					unclear, has homology to DNA binding proteins and an unusual signal sequence
interaction
regulation
MW					32724 Da; 293 aa

D-allose-binding protein precursor (alsB )

function					Part of the binding-protein-dependent transport system alsbac for D-allose
interaction
regulation
MW					32910 Da; 311 aa

Ferrichrome-binding protein precursor (fhuD )

function					involved in high-affinity transport of ironIII -ferrichrome into the cell
interaction
regulation
MW					32998 Da; 296 aa

Iron^III Dicitrate-binding protein precursor (fecB )

function					binds citrate dependent IronIII
interaction
regulation
MW					33120 Da; 300 aa

Hypothetical 33.3 kD Protein in ompX-moeB intergenic region precursor (ybiS )

function
interaction
regulation
MW					33325 Da; 306 aa

Putative L-asparaginase AsgX (ybiK )

function					L-asparagine + H 2O = L-aspartate + NH 3
interaction
regulation
MW					33394 Da; 321 aa

Glutamate/aspartate periplasmic binding protein (gltI )

function					Part of the binding-protein-dependent transport system for glutamate and aspartate. Binds to both aspartate and glutamate
interaction
regulation
MW					33420 Da; 302 aa

Amino-acid ABC transporter binding protein in acrF-rrnD intergenic region precursor (yhdW )

function					probably part of a binding-protein-dependent aa transport system
interaction
regulation
MW					33425 Da; 305 aa

High-affinity zinc binding protein ZnuA (znuA )

function
interaction
regulation
MW					33777 Da; 310 aa

Penicillin-binding protein7 precursor (pbpG )

function					cell wall formation
interaction					penicillin sensitieve
cofactors
regulation
MW					34245 Da; 313 aa

Taurine-binding protein precursor (tauA )

function
interaction
regulation					sulfate starvation induced
MW					34266 Da; 320 aa

Ferrienterobactin-binding protein precursor (fepB )

function					binds ferrienterobactin
interaction
regulation					induction in part controlled by the amount of available iron
MW					34283 Da; 318 aa

32.1 kD protein in ppa-fbp intergenic region precursor (ytfQ )

function					potential monosaccharide transporter
interaction
regulation
MW					34344 Da; 318 aa

Protein ErfK precursor (erfK )

function
interaction
regulation
MW					34411 Da; 310 aa

Sulfonate-binding protein precursor SsuA (ssuA )

function					specifically binds aliphatic sulfonates, involved in transport
interaction
regulation					sulfate starvation induced
MW					34557 Da; 319 aa

Hypothetical 34.6 kD protein in nhd-mfd intergenic region precursor (ycfS )

function
interaction
regulation
MW					34636 Da; 320 aa

Hypothetical periplasmic protein YahB (yahB )

function					unclear, has homology to DNA binding proteins
interaction
regulation
MW					34866 Da; 310 aa

Hypothetical ABC transporter binding protein YphF precursor (yphF )

function					probably part of a binding-protein-dependent transport system YphDEF potentially transporting a monosaccharide
interaction
regulation
MW					35058 Da; 327 aa

FecR protein precursor (fecR )

function					regulates iron dicitrat transport via FecI, sensory transduction
interaction					inactivates FecI in absence of citrate
regulation
MW					35532 Da; 317 aa

L-Arabinose-binding protein precursor (araF )

function					high affinity to arabinose, can also bind D-galactose and D-fucose
interaction
regulation
					3d-structure
MW					35541 Da; 329 aa

D-galactose-binding protein precursor (mglB )

function					involved in the active transport of D-galactose and D-glucose role in chemotaxis
interaction					with Trg chemoreceptor
regulation
					calcium-binding site 3d-structure
MW					35712 Da; 332 aa

D-xylose-binding protein precursor (xylF )

function					binds xylose with high affinity
interaction					energized by high-energy phosphate compounds
regulation					sensitiv to cold osmotic shock
MW					35734 Da; 330 aa

Sigma E factor regulatory protein RseB precursor (rseB )

function					seems to modulate the activity of RpoE
interaction
regulation
MW					35749 Da; 318 aa

Hypothetical 36.0 kD protein in avtA-selB intergenic region precursor (yiaO )

function
interaction
regulation
MW					35970 Da; 328 aa

Hydrogenase-2 operon protein HybA (hybA )

function					periplasmic electron-transferring activity of hydrogenase 2
interaction					HybBO
cofactors					Binds 4 4Fe-4S clusters
regulation
MW					36003 Da; 328 aa

Glycine betaine-binding protein precursor (proX )

function					member of multicomponent binding-protein-dependent transport system
interaction
regulation
MW					36022 Da; 330 aa

Hypothetical 36.1 kD protein in llp-aroD intergenic region precursor (ynhG )

function
interaction
regulation
MW					36082 Da; 334 aa

Thiamine-binding protein precursor (sfuA )

function
interaction
regulation
MW					36163 Da; 327 aa

Hypothetical protein YneA (yneA )

function
interaction
regulation
MW					36685 Da; 340 aa

Sulfate-binding protein precursor (sbp )

function					specifically binds sulfate, involved in transport
interaction
regulation					sulfate starvation induced
MW					36689 Da; 329 aa

L-asparaginase II precursor (ansB )

function					aspartate synthesis Catalytic activity: L-asparagine + H2O = L-aspartate + NH3
interaction
cofactors
regulation					induction by cAMP and anaerobiosis
					homotetramer 3d-structure
MW					36850 Da, 348 aa

Potential binding protein for amino acids (yhdW )

function					Putative amino-acid binding protein
interaction
regulation
MW					37020 Da; 341 aa

Phosphate-binding protein precursor (pstS )

function					BP mediated phosphate transport
interaction
regulation					induction by phosphate deprivation, subject to positive control by PhoB and negative control by PhoR
					3d-structure
MW					37024 Da; 346 aa

Phosphonates-binding protein precursor (phnD )

function					alkylophosphonates binding protein
interaction
regulation
MW					37370 Da; 338 aa

Thiosulfate-binding protein precursor (cysP )

function					binding and transmembrane transport
interaction
regulation
MW					37614 Da; 338 aa

Protein TorT (torT )

function					role in torCAD operon induction
interaction					binds putative inducer, interacts with TorS
regulation
MW					37864 Da; 342 aa

Flagella P-Ring Protein precursor (flgI )

function					part of basal body
interaction
regulation
MW					38169 Da; 365 aa

Mutarotase (galM )

function					Aldose 1-epimerase, converts alpha-aldose to the beta-anomer. Acts on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose.
interaction
regulation
MW					38190 Da; 346 aa

Spermidine/putrescine-binding protein precursor SPBP (potD )

function					polyamine-binding protein
interaction
regulation
					3d-structure
MW					38867 Da; 348 aa

Leu/Ile/Val-binding protein LIV-BP precursor (livJ )

function					component of leucine, isoleucine, valine (threonine) transport
interaction
regulation
					3d-structure
MW					39076 Da; 367 aa

Cytochrome c-type biogenesis protein CcmH precursor (ccmH )

function					may be required in biogenesis of c-type cytochrome, possible subunit of heme lyase
interaction
regulation
					39089 Da; 350 aa

Leucine-specific binding protein precursor (livK )

function					component of the leucine-specific transport system
interaction
regulation
					3d-structure
MW					39306 Da; 369 aa

Hydrogenase-2 small chain HybO (hybO )

function					NiFe hydrogenase Membrane-bound hydrogenase 2 small subunit
interaction					HybAC
cofactors					Binds two 4Fe-4S clusters and one 3Fe-4S cluster
regulation
MW					39652 Da; 372 aa

40 - 50 kDa

Putrescine-binding protein precursor (potF )

function					polyamine-binding protein
interaction
regulation
MW					40839 Da; 370 aa

Glycerophosphoryl diester posphodiesterase precursor (glpQ )

function					multigene fam., hydrolyzes deacylated phospholiopids Catalytic activity: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate
interaction
cofactors
regulation
MW					40843 Da; 358 aa

Penicillin acylase precursor (ampC )

function					penicillin resistance Catalytic activity: beta-lactam + H2O = a substituted beta-amino acid the N4-C7 bond of the lactam ring is cleaved
interaction
cofactors
regulation
					monomer 3d-structure
MW					41555 Da; 377 aa

Penicillin-binding protein AmpH (ampH )

function					Binds penicillin & belongs to the beta-lactamase family
interaction
cofactors
regulation
MW					41849 Da; 385 aa

Potential polyamine binding protein (ydcS )

function
interaction
regulation
MW					42295 Da; 381 aa

Potential binding protein (ynjB )

function
interaction
regulation
MW					42844 Da; 388 aa

Maltose-binding protein MBP precursor (malE )

function					binds maltoligosaccharides, involved inhigh affinity maltose-transport system, chemotaxis
interaction					with MalF and MalG
regulation
					3d-structure
MW					43387 Da; 396 aa

Penicillin-binding protein 6 precursor (dacC )

function					D-alanine carboxypeptidase Removes C-terminal d-ala residues from sugar-peptide cell wall precursors Belongs to Ser protease family S11
interaction
cofactors
regulation
MW					43609 Da; 400 aa

Penicillin-binding protein5 precursor (dacA )

function					D-alanine carboxypeptidase Removes C-terminal d-ala residues from sugar-peptide cell wall precursors Belongs to Ser protease family S11
interaction
cofactors
regulation
MW					44444 Da; 403 aa

Glucose-1-phosphatase precursor (agp )

function					required for growth in high phosphate with G-1-P as sole carbon source Catalytic activity: D-glucose 1-phosphate + H2O = D-GLUCOSE + orthophosphate
interaction
cofactors
regulation					independent from inorganic phosphate availability, catabolite repression, positively by cAMP/CRP,
					homodimer
MW					45683 Da; 413 aa

TolB protein precursor (tolB )

function					involved in the TonB-independent uptake of a group of colicins
interaction
regulation
					3d-structure
MW					45955 Da; 430 aa

Potential binding protein (ycjN )

function
interaction
regulation
MW					46808 Da; 430 aa

pH 2.5 acid phosphatase precursor (appA )

function					Catalytic activity: an orthophosphoric monoester + H2O = an alcohol + orthophosphate
interaction
cofactors
regulation					cAMP regulated, induced when reaching stationary phase, synthesis triggered by phosphate starvation or shift from aerobic to anaerobic condit.
					monomer
MW					47056 Da; 432 aa

Protease DegQ precursor (hhoA )

function

shared specificity with HtrA/DegP

interaction

cofactors

regulation

MW

47205 Da; 455 aa

Survival protein SurA precursor (surA )

function					folding of extracytoplasmic proteins, essential in stationary phase
interaction
cofactors
regulation
MW					47283 Da; 428 aa

Putative beta-lactamase YfeW (yfeW )

function
interaction
cofactors
regulation
MW					47752 Da; 434 aa

Glycerol-3-phosphate-binding protein precursor (ugpB )

function					sn-glycerol-3-phosphate and glycerophosphoryl diester-binding
interaction					UgpACE
regulation
MW					48452 Da; 438 aa

Alkaline phosphatase precursor (phoA )

function					Broad spectrum dephosphorylating enzyme
interaction
cofactors					metalloenzyme containing two zinc atoms and a magnesium ion
regulation
					three isoforms 3d-structure Extensively used as a reporter enzyme and in gene fusion experiments
MW					49438 Da; 471 aa

Protease DegP (Do) precursor (htrA )

function					required at high temp., degradation of damaged prot., chaperone activity at low temperature, shared specificity with DegQ
interaction
cofactors
regulation					induction by heat shock
					multimeric; 2 PDZ domains
MW					49439 Da; 474 aa

50 - 60 kDa

Penicillin-Binding Protein 4 precursor (dacB )

function					final stages in peptidoglycan synthesis
interaction					penicillin sensitive
cofactors
regulation
MW					51798 Da; 477 aa

SufI Protein precursor (sufI )

function					involved in cell division, supresses a ftsI mutation
interaction
regulation
MW					51858 Da; 470 aa

Cytochrome c₅₅₂precursor (nrfA )

function					terminal reductase of the formate-dependent pathway for nitrite reduction to ammonia interactions
interaction					binds five heme groups per molecule
regulation					induction in presence of nitrite, subject to glucose and nitrate repression
MW					53703 Da; 478 aa

55.5 kD protein in kdgK-dctA intergenic region precursor (yhjJ )

function					metalloprotease
interaction
cofactors					binds zinc?
regulation
					has lost the active site residues
MW					55527 Da; 498 aa

Putative binding protein YliB (yliB )

function					Probably part of the binding-protein-dependent transport system yliABCD
interaction
cofactors
regulation
MW					56470 Da; 512 aa

Probable 53.4 kD blue copper protein precursor YacQ (yacK )

function					Multicopper oxidase
interaction
cofactors
regulation
					homodimer
MW					56556 Da; 516 aa

Potential binding protein (yddS )

function
interaction
regulation
MW					57641 Da; 516 aa

Glucans Biosynthesis Protein MdoG precursor (mdoG )

function					involved in MDO synthesis
interaction
regulation
MW					57912 Da; 511 aa

Nickel-binding protein precursor (nikA )

function					probably binds nickel
interaction
regulation
MW					58719 Da; 524 aa

Murein peptide-binding protein precursor (mppA )

function					binds L-alanyl-gamma-d-glutamyl-meso-diaminopimelate with high affinity
interaction
regulation
MW					59900 Da; 537 aa

60 - 70 kDa

Dipeptide transport protein precursor (dppA)

function					dipeptide-binding, required for chemotaxis
interaction
regulation					osmotic shockable transport system
					3d-structure
MW					60293 Da; 535 aa

Polysialic acid transport protein KpsD precursor (KSD5) (kpsD )

function					involved in translocation of PSA across OM, binds polysaccharide
interaction
regulation
MW					60484 Da; 558 aa

Potential binding protein (ygiS )

function
interaction
regulation
MW					60694 Da; 535 aa

UDP-sugar hydrolase precursor (ushA )

function					multifunctional: hydrolase, 5'-Nucleotidase Catalytic activity 1: UDP-sugar + H(2)O = UMP + sugar 1-phosphate. Catalytic activity 2: A 5'-ribonucleotide + H(2)O = A ribonucleoside + orthophosphate
interaction
cofactors					Binds two Zn2+; Co2+ for Nucleotidase
regulation					inhibition by an intracellular protein inhibitor
MW					60824 Da; 550 aa

Oligopeptide-binding protein precursor (oppA )

function					component of the oligopeptide permease, binds oligopeptides up to five amino acids with high affinity
interaction
regulation
MW					60899 Da; 543 aa

Glucans biosynthesis protein D (mdoD )

function					Probably involved in the control of the structural glucose backbone of MDOs, MdoG homologue
interaction
regulation
MW					62758 Da; 551 aa

Peptide transport protein SapA precursor (sapA )

function					involved in peptide intake transport system that plays a role in resistance to antimicrobial peptides
interaction
regulation
MW					61564 Da; 547 aa

Aminoacyltransferase precursor (ggt )

function					role in glutathion degradation & synthesis,(g-Glutamyl cycle) Catalytic activity: (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl-amino acid
interaction
cofactors
regulation
					consists of two polypeptide chains, which are synthesised from a single polypeptide
MW					61768 Da, 580 aa

Hydrogenase-2 large chain (hybC )

function					NiFe hydrogenase, H2 + A = AH 2
interaction					Heterodimer of a large and a small subunit
cofactors					Binds 1 nickel ion per subunit
regulation
MW					62360 Da; 566 aa

Putative sulfatase YdeN (ydeN )

function					belongs to the sulfatase family
interaction
cofactors
regulation
MW					62802 Da; 560 aa

Trehalase precursor (treA )

function					hydrolyses alpha- 1,1 glycosidic bond in trehalose
interaction
cofactors
regulation					slightly induced by high osmolarity and stationary phase
MW					63636 Da; 565 aa

NiFe hydrogenase subunit (hyaB )

function					Membrane-bound hydrogenase 1 large subunit, catalytic activity: H 2+ A = AH 2
interaction
cofactors
					might be cotranslocated with HyaA which has a proper TAT signal sequence
MW					66253 Da; 579 aa

AsmA Protein precursor (asmA )

function					involved in inhibitionof assembly of mutant OmpF proteins, could be involved in OM protein assembly
interaction
regulation
MW					68962 Da; 617 aa

Potential binding protein (yejA )

function
interaction
regulation
MW					69669 Da; 604 aa

60 - 70 kDa

2',3'-Cyclic-nucleotide 2'-phosphodiesterase precursor (cpdB )

function					bifunctional, catalyzes two consecutive reactions converting 2',3'-cyclic-nucleotide to 3'-nucleotide and then 3'-nucleotide to nucleic acid and phosphate
interaction
cofactors
regulation
					two distinguishable active sites
MW					70832 Da; 647 aa

Lytic murein transglycosylase precursor (slt )

function					Murein-degrading, may play role in recaycling muropeptides during cell elongation and/or cell division
interaction					energy conserving reaction
cofactors
regulation
					tightly associated with murein sacculus 3d-structure
MW					73369 Da; 645 aa

Biosynthetic arginine decarboxylase precursor (ADC) (speA )

function					biosynthetic and biodegradative form, first step in the spermidine synthesis from arginine, the biodegradive form may ply a role in regulating pH by consuming proteins
interaction
cofactors					pyridoxal phosphate and Mg2+
regulation					induction: growth in acidic enriched medium containing arginine (biodegr.), growth in MMA at neitral pH (biosynth.), repression of speA and feedback inhibition of ADC by putrescine and spermidine,
					homotetramer
MW					73983 Da; 658 aa

Alpha-amylase precursor (malS )

function					Alpha-amylase; degradation of maltooligosaccharides with a preference for chain length longer than 6 glucose units
interaction
cofactors
regulation					MalT (maltose regulon)
					monomer 2 disulfide bonds
MW					75712 Da; 676 aa

Tail specific protease precursor (prc )

function					selectively degrades proteins with nonpolar C- terminus (that arises for example from the action of 10sRNA), PBP3 maturation
interaction
cofactors
regulation
MW					76663 Da; 682 aa

80 - 90 kDa

Beta-glucosidase precursor (bglX )

function					hydrolysis of terminal non-reducing beta-D glucose residues
interaction
cofactors
regulation
MW					83460 Da; 765 aa

Copper amine oxidase precursor (maoA )

function					initial steps of 2-phenylethylamine catabolism Catalytic activity: 2-Phenylethylamine + H2O + O2 = Phenylacetaldehyde + NH3 + H2O2
interaction
cofactors					copper and topaquinon
regulation
					homodimer 3D-structure
MW					84378 Da; 757 aa

Hypothetical protein YgjK (ygjK )

function
interaction
cofactors
regulation
MW					88321 Da; 783 aa

Putative dimethyl sulfoxide reductase chain YnfE (ynfE )

function					DMSO reductase
interaction					with YfnF and YfnG
cofactors					Molybdenum (molybdopterin); may bind a 4Fe-4S cluster
regulation
MW					89780 Da; 808 aa

Putative dimethyl sulfoxide reductase chain YnfF (ynfF )

function					DMSO reductase
interaction					with YfnE and YfnG
cofactors					Molybdenum (molybdopterin); may bind a 4Fe-4S cluster
regulation
MW					89987 Da; 807 aa

90 - 100 kDa

Nitrate reductase precursor (napA )

function					a role in anaerobic growth with limiting concentrations of nitrate, large subunit of the periplasmic nitrate reductase (NAP) Catalytic activity: nitrite + acceptor = nitrate + reduced acceptor
interaction
cofactors					molybdopterin guanine dinucleotide (MGD)
regulation					expressed during anaerobic growth (via FNR), further induction by low concentrations of nitrate (via NarP)
MW					93042 Da; 828 aa

Trimethylamine-N-oxide reductase precursor (torA )

function					reduces trimethylamine-n-oxide into trimethylamine, an anaerobic reaction coupled to energy yielding reaction Catalytic activity: NADH + Trimethylamine-N-Oxide = NAD+ + Trimethylamine + H2O
interaction
cofactors
regulation
					contains molybdopterin
MW					94456 Da; 848 aa

Penicillin acylase precursor (pac )

function					penicillin resistance Catalytic activity: penicillin + H2O = a fatty acid anion + 6-aminopenicillanate
interaction
cofactors
regulation
					heterodimer 3d-structure
MW					94642 Da; 846 aa

Probable bifunctional chitinase/lysozyme precursor (chiA )

function					hydrolysis of [[beta]]-1,4 glucosidic linkages between N-acetylmuramic acid and N-acetylglucosamine and/or chitin degradation
interaction
cofactors
regulation
MW					97057 Da; 897 aa

Above 100 kDa

ProteaseIII precursor (ptr )

function					May prefer small substrates
interaction
cofactors					requires divalent cations, binds Zn2+
regulation
					monomer
MW					107708 Da; 962 aa

Formate dehydrogenase alpha subunit FdnG (fdnG )

function
interaction
cofactors					1 molybdenum ion, 2 molybdopterin guanine dinucleotide (MGD) groups, 1 4Fe-4S cluster, and 1 selenocysteine per subunit
regulation
MW					112916 Da; 1015 aa