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ecce/ proteins of the inner membrane/ others

Chaperones
Protein Anchors
Lipoproteins
Antibiotic Resistance (other than transport)
Organelle Shape
Involved in Phage Growth




Chaperones

DnaJ like protein DjlA (djlA )
function 
interaction 
regulation 
topologytransmembrane domains: 1 (potential)

TMHMM gives 7-29
SP gives 7-27

mqywgkIIGV AVALLMGGGF WGVVLGLLIg hmfdkarsrk mawfanqrer
qalffattfe vmghltkskg rvteadihia sqlmdrmnlh gasrtaaqna
frvgksdnyp lrekmrqfrs vcfgrfdlir mfleiqiqaa fadgslhpne
ravlyviaee lgisraqfdq flrmmqggaq fgggyqqqtg ggnwqqaqrg 200
ptledacnvl gvkptddatt ikrayrklms ehhpdklvak glppemmema
kqkaqeiqqa yelikqqkgf k

MW 30579 Da; 271 aa


Protein Anchors

Fumarate reductase 15 kD hydrophobic protein (frdC )
functionmay be required to anchor the catalytic components of the fumarate reductase complex to cytoplasmic membrane
part of an enzyme complex containing four subunits
interaction 
regulation 
topologytransmembrane domains: 3 (potential)

TMHMM gives 27-49 69-91 112-130
SP gives 30-50 63-83 109-129

mttkrkpyvr pmtstwwkkl pfyrfyMLRE GTAVPAVWFS IELIFGLFAL
kngpeawagf vdflqnpvIV IINLITLAAA LLHTKTWFel apkaaniivk
dekmgpepii kSLWAVTVVA TIVILFVALY w

MW 15015 Da; 131 aa


Fumarate reductase 13 kD hydrophobic protein (frdD )
functionmay be required to anchor the catalytic components of the fumarate reductase complex to cytoplasmic membrane
part of an enzyme complex containing four subunits
interaction 
regulation 
topologytransmembrane domains: 3 (potential)

TMHMM gives 13-46 56-78 99-118
SP gives 13-40 55-80 99-119

minpnpkrsd epvfwglfga ggMWSAIIAP VMILLVGILL PLGLFPgdal
syervLAFAQ SFIGRVFLFL MIVLPLWCgl hrmhhamhdl kihvpagkWV
FYGLAAILTV VTLIGVVTi

MW 13107 Da; 119 aa


> Succinate dehydrogenase hydrophobic membrane anchor protein (dhsD )
functionmay be required to anchor the catalytic components of the succinate dehydrogenase complex to cytoplasmic membrane
part of an enzyme complex containing four subunits
interaction 
regulation 
topologytransmembrane domains: 3 (potential), SP has 4

TMHMM gives 16-38 48-70 91-113
SP gives 16-36 37-57 59-79 95-115

mvsnasalgr ngvhdFILVR ATAIVLTLYI IYMVGFFAts geltyevWIG
FFASAFTKVF TLLALFSILI hawigmwqvl tdyvkplalr LMLQLVIVVA
LVVYVIYGFV VVWgv

MW 12867 Da; 115 aa


Anaerobic dimethyl sulfoxide reductase chain C (dmsC )
functionanchors the two other subunits to the membrane and stabilizes the catalytic subunits
part of an enzyme complex consisting of three subunits (DmsA, DmsB, DmsC)
interaction 
regulation 
topologytransmembrane domains: 8 (potential)

TMHMM gives 10-32 45-67 82-104 117-134 149-171 184-206 226-243 255-277
SP gives 10-32 44-66 90-107 115-134 157-174 183-201 225-242 255-280

mgsgwhewpL MIFTVFGQCV AGGFIVLALA LLkgdlraea qqrvIACMFG
LWVLMGIGFI ASMLHLGspm rafnslnrvg aSALSNEIAS GSIFFAVGGI
GWLLamlkkl spalrtLWLI VTMVLGVIFV WMMVrvynsi dtvptwysIW
TPMGFFLTMF MGGPLLGYLL Lslagvdgwa mrlLPAISVL ALVVSGVVSV 200
MQGAELatih ssvqqaaalv pdygaLMSWR IVLLAVALCL WIApqlkgyq
pavpLLSVSF ILLLAGELIG RGVFYGLhmt vgmavas

MW 30826 Da; 287 aa


Lipoproteins

Lipoprotein-28 precursor (nlpA )
function 
interaction 
regulation 
topologyattached to the inner membrane by a lipid anchor
MW 29423 Da; 272 aa


Lipoproptein NlpD precursor (nlpD )
functionmay be involved in stationary-phase survival
interaction 
regulation 
topologyattached to the inner membrane by a lipid anchor
MW 40149 Da; 379 aa


Antibiotic Resistance, Other Than Transport

Tellurite resistance protein (tehA )
functionwhen present in high copy number responsible for potassium tellurite resistance
interaction 
regulation 
topologytransmembrane domains: 8 (potential)

TMHMM gives 7-29 44-66 79-101 157-179 200-219 229-247 254-276 286-308
SP gives 6-26 40-60 81-101 103-123 140-160 164-184 201-221 283-303

mqsdkvLNLP AGYFGIVLGT IGMGFAWrya sqvwqvshwl gdgLVILAMI
IWGLLTSAFI ARLIrfphsv laevrhpvLS SFVSLFPATT MLVAIGFVPW
Frplavclfs fgvvvqlaya awqtaglwrg shpeeattpg lylptvannf
isamacGALG YTDAGLVFLG AGVFSWLSLe pvilqrlrss gelptalrtS 200
LGIQLAPALV ACSAWLSVng gegdtlakML FGYGLLQLLF MLRLMPWyls
qpfnASFWSF SFGVSALATT GLHLGSgsdn gffhtLAVPL FIFTNFIIAI
LLIRTFALLM qgkllvrter avlmkaedke

MW 35932 Da; 330 aa


Organelle Shape

Curli production assembly/transport component CsgG (csgG )
functionmay be involved in biogenesis of curli organelles
interaction 
regulation 
topologyattached to membrane by lipid anchor
MW 30557 Da; 277 aa


Involved in Phage Growth

HflK protein (hflK )
functionHflK and HflC govern the stability of phage lambda cII protein and have been proposed to to encode or regulate a cII specific protease
interactionHflK and HflC may interact to form a multimeric complex
regulation 
topologytransmembrane domains: 1 (potential)

TMHMM gives 76-98
SP gives 80-100

mawnqpgnng qdrdpwgssk pggnsegngn kggrdqgppd lddifrklsk
klgglgggkg tgsgggsssq gprpqlggrV VTIAAAAIVI IWAASGFYti
keaergvvtr fgkfshlvep glnwkptfid evkpvnveav relaasgvml
tsdenvvrve mnvqyrvtnp ekylysvtsp ddslrqatds alrgvigkyt 200
mdriltegrt virsdtqrel eetirpydmg itlldvnfqa arppeevkaa
fddaiaaren eqqyireaea ytnevqpran gqaqrileea raykaqtile
aqgevarfak llpeykaape itrerlyiet mekvlgntrk vlvndkggnl
mvlpldqmlk ggnapaaksd ngasnllrlp passsttsga sntsstsqgd 400
imdqrranaq rndyqrqge

MW 45545 Da; 419 aa


Bacteriophage T4 late gene expression blocking protein (lit )
functioninteracts with a short DNA sequence about one-quarter of the way into the major capsid protein gene 23 of T4, inhibition occurs when this late gene of T4 is expressed
interaction 
regulation 
topologytransmembrane domains: 0 (potential), SP has 2

TMHMM gives 0
SP gives 61-82 149-178
mrspichlfs ainsspfkia pekeqdlkti vddkkiiisv vsepgfnirv
rknesnnshe ivltvasley iwafsnffwv ftqeysksqk nndehfdltg
knrlkksdel lkwarknlqt tgceswpkkc pkpeaylqgs edsqvaseif
lcaiawilhh eishvvlqhp lvttafstqe ereadshatk wilgnlyesa 200
pelkkralgi atavlciqsl evenyfclqn thpaayeriy sniscypvgn
eeliealctv mlqylfhgkn invnldgesf ssilgdllcd isrltsn

MW 33762 Da; 297 aa


Bacteriophage N4 adsorption protein B (nfrB )
functionrequired for phage adsorption, may be a component of phage receptor
interaction 
regulation 
topologytransmembrane domains: 4 (potential), SP has 3

TMHMM gives 20-42 361-383 393-415 422-444
SP gives 8-28 362-382 393-413

mdwlldVFAT WLYGLKVIAI TLAVIMFIsg lddffidvvy wvrrikrkls
vyrryprmsy relykpdekp laimvpawne tgvignmael aattldyeny
hifvgtypnd pdtqrdvdev carfpnvhkv vcarpgptsk adclnnvlda
itqfersanf afagfilhda edvispmelr lfnylverkd liqipvypfe 200
rewthftsmt yidefselhg kdvpvreala gqvpsagvgt cfsrravtal
ladgdgiafd vqsltedydi gfrlkekgmt eifvrfpvvd eakereqrkf
lqhartsnmi cvreyfpdtf stavrqksrw iigivfqgfk thkwtssltl
nyflwrdrkg AISNFVSFLA MLVMIQLLLL LAYeslwpda whFLSIFSGS 400
AWLMTLLWLN FGLMVnrivq rVIFVTGYYG LTQGLLSVLr lfwgnlinfm
anwralkqvl qhgdprrvaw dktthdfpsv tgdtrslrpl gqillenqvi
teeqldtalr nrveglrlgg smlmqglisa eqlaqalaeq ngvawesida
wqipssliae mpasvalhya vlplrlende livgsedgid pvslaaltrk 600
vgrkvryviv lrgqivtglr hwyarrrghd pramlynavq hqwlteqqag
eiwrqyvphq flfaeilttl ghinrsainv lllrherssl plgkflvteg
visqetldrv ltiqrelqvs mqslllkagl nteqvaqles enege

MW 85319 Da; 745 aa


Rtn protein (rtn )
functioninvolved in the resistance to phages T4 and lambda
interaction 
regulation 
topologytransmembrane domains: 2 (potential)

TMHMM gives 12-34 236-258
SP gives 16-36 236-256

mfirapnfgr kLLLTCIVAG VMIAILVSCL QFLVawhkhe vkydtlitdv
qkyldtyfad lksttdrlqp ltldtcqqan peltaraafs mnvrtfvlvk
dkktfcssat gemdiplnel ipaldinknv dmailpgtpm vpnkpaiviw
yrnpllknsg vfaalnlnlt pslfyssrqe dydgvaliig ntalstfssr 200
lmnvneltdm pvretkiagi pltvrlyadd wtwndVWYAF LLGGMSGTVV
GLLCYYLMsv rmrpgreimt aikreqfyva yqpvvdtqal rvtglevllr
wrhpvageip pdafinfaes qkmivpltqh lfeliardaa elekvlpvgv
kfginiapdh lhsesfkadi qklltslpah hfqivleite rdmlkeqeat 400
qlfawlhsvg veiaiddfgt ghsaliyler ftldylkidr gfinaigtet
itspvldavl tlakrlnmlt vaegvetpeq arwlsergvn fmqgywisrp
lplddfvrwl kkpytpqw

MW 58588 Da; 518 aa