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ecce/ outer membrane proteins/ listed by size

---Up to 20 kDa
---20 - 30 kDa
---30 - 40kDa
---40 - 50 kDa
---50 - 60 kDa
---60 - 80 kDa
---80 - 90 kDa
---90 - 100 kDa
---Above 100 kDa




Up to 20 kDa



(b1369) ENTREZ AAC74451
functionhypothetical outer membrane protein
interaction 
regulation 
MW5888 Da; 51 aa


Major outer membrane lipoprotein precursor (lpp )
function 
interaction 
regulation 
 attached to the membrane by a lipid anchor
3d-structure
MW8323 Da; 78 aa


Hypothetical 9.5 kD lipoprotein in metC-sufI intergenic region (yqhH )
function 
interaction 
regulation 
 attached to the outer membrane by a lipid anchor
MW9513 Da; 85 aa

(b1966) ENTREZ AAC75032
functionputative outer membrane protein
interaction 
regulation 
MW15099 Da; 134 aa


Outer membrane lipoprotein SlyB precursor (slyB )>
function 
interaction 
regulation 
 attached to the membrane by a lipid anchor
MW15602 Da; 155 aa


ENTREZ AAC75056 (b1995)
functionhypothetical outer membrane protein
interaction 
regulation 
MW15653 Da; 139 aa


GspH
functionPUTATIVE GENERAL SECRETION PATHWAY PROTEIN H
interaction 
regulation 
MW18565 Da; 169 aa


Outer membrane protein X precursor (ompX )
function 
interaction 
regulation 
 transmembrane domains: 8 (potential)
MW18603 Da; 171 aa


Peptidoglycan-associated lipoprotein precursor (pal )
functionstrongly associated with the peptidoglycan
interaction 
regulation 
 attached to the membrane by a lipid anchor
MW18824 Da; 173 aa


Outer membrane lipoprotein Blc precursor (blc )
functionmay serve a starvation response
interaction 
regulation 
 attached to the membrane by a lipid anchor
MW19851 Da; 177 aa



20 - 30 kDa


outer membrane protein Slp precursor (slp )
functionmay help to stabilize the outer membrane during carbon starvation and stationary phase
interaction 
regulationinduced upon starvation and slowed growth, cAMP/CRP-independent
 attached to the membrane by a lipid anchor
MW20964 Da; 188 aa


yiaD
functionputative lipoprotein IN BISC-CSPA INTERGENIC REGION
interaction 
regulation 
MW22169 Da; 219 aa


Hypothetical 22.9 kD Protein in tonB-trpA intergenic region precursor (yciD )
function 
interaction 
regulation 
MW22928 Da; 212 aa


Flagellar L-ring protein precursor (flgH )
functionpart of the basal body of the flagellar organelle
interaction 
regulation 
 attached to the outer membrane by a lipid anchor
MW24615 Da; 232 aa


Copper homeostasis protein CutF precursor; (LIPOPROTEIN NlpE) (cutF )
functioninvolved in copper homeostasis, could be involved in both copper efflux and the delivery of copper to copper-dependent enzymes
interaction 
cofactors 
regulation 
 attached to the outer membrane by a lipid anchor
MW25844 Da; 236 aa


Membrane-bound lytic murein Transglycosylase E precursor (mltE )
functionmurein-degrading enzyme, may play a role in recycling of muropeptides during cell elongation and/or cell division
interaction 
cofactors 
regulation 
MW26574 Da; 241 aa


Hypothetical 27.4 kD Protein in avtA-selB intergenic region precursor (yiaT )
function 
interaction 
cofactors 
regulation 
MW27413 Da; 246 aa


Hypothetical 27.8 kD Protein in gapA-rnd intergenic region precursor (yeaF )
function 
interaction 
regulation 
MW27831 Da; 248 aa


VacJ lipoprotein precursor (vacJ )>
function 
interaction 
regulation 
 attached to the membrane by a lipid anchor
MWattached to the membrane by a lipid anchor
28041 Da; 251 aa


Phosphatidylglycerophosphatase B (pgpB )
functionhydrolyzes phosphatidylglycerophosphate, phosphatidic acid and lysophosphatic acid, the pattern of activities varies according to subcellular location
interaction 
cofactors 
regulation 
 integral membrane protein of the inner and the outer membrane
MW29021 Da; 254 aa



nlpA
functionputative lipoprotein
interaction 
regulation 
MW29423 Da; 272 aa


yaeC
functionputative lipoprotein
interaction 
regulation 
MW29431 Da; 271 aa


30 - 40 kDa


ENTREZ AAC75397 (b2337)
functionputative outer membrane protein, homologous to PapC/E. coli
interaction 
regulation 
MW31643 Da; 298 aa


Phospholipase A1 precursor (pldA )
functionhydrolysis of phosphatidylcholine with phospholipase A2 and phospholipase A1 activities. Required for efficient secretion of bacteriocins, seems to be dormant in normal growing cells
interaction 
cofactorsrequires calcium ions for activity
regulationinduction: by membrane damaging, e.g. phage-induced lysis or temperature shock
MW33163 Da; 289 aa


Nucleoside-specific channel-forming protein Tsx precursor (tsx )
functionsubstrate-specific channel for nucleosides and deoxynucleosides
receptorfor colicin K and bacteriophage T6
interaction 
regulation 
MW33589 Da; 294 aa


Outer membrane protein G precursor (ompG )
function 
receptor 
interaction 
regulation 
 monomer
large channel
MW34913 Da; 301 aa


Outer membrane protease OmpP precursor (ompP )
functionprotease, also acts as receptor for bacteriophage Ox2
interaction 
cofactors 
regulation 
 homopentamer
MW35499 Da; 315 aa


Protease VII Precursor (ompT )
functioncleaves T7 RNA polymerase, ferric enterobactin receptor protein and other proteins, specificity for paired basic residues
interaction 
cofactors 
regulationinhibited by zinc ions
 homopentamer
MW35562 Da; 317 aa


Lipoprotein-34 precursor (nlpB )
functionnon-essential lipoprotein
interaction 
regulation 
 attached to the membrane by a lipid anchor
&MW36842 Da; 344 aa


Outer membrane protein A precursor (ompA )
functionrequired for the actions of colicins K and L and for the stabilization of mating aggregates in conjugation
receptorfor a number of T-even like phages
interaction 
regulation 
 monomer
3d-structure
spans the membrane 8 times
MW37201 Da; 346 aa


Outer membrane pore protein E precursor (phoE )
functionpore for efficient uptake of inorganic phosphate, phosphorylated compounds and some negatively charged solutes
receptor 
interaction 
regulationinduced when cells are grown under phosphate limitation
 homotrimer
3d-structure
spans the membrane 16 times
MW38922 Da; 351 aa


Outer membrane protein F precursor (ompF )
functionpassive diffusion pore for small molecular weight hydrophilic materials
receptorfor bacteriophage T2
interaction 
regulation 
 homotrimer
3d-structure
spans the membrane 16 times
MW39333 Da; 362 aa



40 - 50 kDa



Membrane-bound lytic murein Transglycosylase C precursor (mltC )
functionmurein-degrading enzyme, may play a role in recycling of muropeptides during cell elongation and/or cell division
interaction 
cofactors 
regulation 
 attached to the outer membrane by a lipid anchor (probable)
MW40112 Da; 359 aa


Membrane-bound lytic murein Transglycosylase B precursor (mltB )
functionmurein-degrading enzyme, may play a role in recycling of muropeptides during cell elongation and/or cell division
interaction 
cofactors 
regulation 
 attached to the outer membrane by a lipid anchor and exposed to the periplasmic side (probable)
MW40256 Da; 361 aa


Outer membrane porin protein NmpC precursor (nmpC )
function 
interaction 
receptor 
regulation 
 in wild-type strains of e.coli K12 the nmpC open reading frame is interrupted by an IS5 insertion and generates a hybrid open reading frame that is not expressed
however in mutant strain CS348 the IS6 element has been deleted ane nmpC is expressed
MW40316 Da; 344 aa


Outer membrane protein C precursor (ompC )
functionpassive diffusion pore for small molecular weight hydrophilic materials
receptorfor bacteriophage ???
interaction 
regulation 
 homotrimer
MW40368 Da; 367 aa


Membrane-bound lytic murein Transglycosylase A precursor (mltA )
functionmurein-degrading enzyme, may play a role in recycling of muropeptides during cell elongation and/or cell division
interaction 
cofactors 
regulationoptimal activity is between pH 4.0 and 4.5, loses its activity rapidly above 30°C
 attached to the outer membrane by a lipid anchor (probable)
MW40410 Da; 365 aa


ENTREZ AAC76082 (b1377)
functionputative outer membrane protein
interaction 
regulation 
MW41220 Da; 377 aa


b1505ENTREZ AAC74578
functionputative outer membrane protein
interaction 
regulation 
MW41616 Da; 382 aa


Putative polysaccharide export protein YccZ precursor (yccZ )
functionmay be involved in polysaccharide transport
interaction 
regulation 
MW41740 Da; 379 aa


Putative polysaccharide export protein Wza precursor (wza )
functionmay be involved in polysaccharide transport
receptor 
interaction 
regulation 
MW41910 Da; 379 aa


Protein transport protein HofQ precursor (hofQ )
function 
interaction 
cofactors 
regulation 
MW44716 Da; 412 aa


Hypothetical 46.1 kD Protein in modC-bioA intergenic region precursor (ybhC )
function 
interaction 
regulation 
 attached to the membrane by a lipid anchor
MW46082 Da; 427 aa


Long-chain fatty acid transport protein precursor (fadL )
functioninvolved in translocation of long-chain fatty acids across the outer membrane
receptorfor bacteriophage T2
interaction 
regulationinduction by long-chain fatty acids, expression of fadL is under control of FadR repressor
MW48857 Da; 448 aa


Membrane-bound lytic murein Transglycosylase D precursor (mltD )
functionmurein-degrading enzyme, may play a role in recycling of muropeptides during cell elongation and/or cell division
interaction 
cofactors 
regulationoptimal activity is between pH 4.0 and 4.5, loses its activity rapidly above 30°C
 attached to the outer membrane by a lipid anchor (probable)
MW49417 Da; 452 aa


Maltoporin precursor (lamB )
functioninvolved in the transport of maltose, maltodextrines and trehalose
interaction 
receptorfor several bacteriophages including lambda and Tp1
regulationMalT dependent, inducer is maltotriose
structurehomotrimer
3d-structure
spans the membrane 18 times
MW49912 Da; 446 aa



50 - 60 kDa



ylcB (o457)ENTREZ AAC73673
functionputative resistance protein
interaction 
regulation 
MW50270 Da; 457 aa


YjcP
functionHYPOTHETICAL 53.4 KDA PROTEIN IN FDHF-ALSK INTERGENIC REGION; similar toPseudomonas cepacia fusaric acid resistance protein FusA
interaction 
regulation 
MW77261 Da; 700 aa


Outer membrane protein TolC precursor (tolC )
functionouter membrane component of several efflux pumps (Acr, Emr, Col, Hly). Involved in multiple drug, detergent and dye resistance. Also involved in extracellular secretion of virulence factors, toxins and colicins.
receptorPhage U3
interactionwith efflux pumps
regulation 
structure3d-structure
homotrimer
each monomer spans the membrane 4 times
has large helical periplasmic domains
MW54014 Da; 495 aa



60 - 80 kDa


ytfM
functionHYPOTHETICAL 64.8 KDA PROTEIN IN MSRA-CHPBI INTERGENIC REGION
interaction 
regulation 
MW64796 Da; 577 aa


Vitamin B12 receptor precursor (btuB )
functionreceptor for cobalmin and bacteriophage Bf23, necesarry for the uptake of E colicins
interaction 
receptorfor cobalmin and bacteriophage Bf23
regulation 
MW68407 Da; 614 aa


Probable general secretion pathway protein D precursor (gspD )
functioninvolved in a general secretion pathway for the export of proteins
interaction 
cofactors 
regulation 
MW71146 Da; 654 aa


Colicin I receptor precursor (cirA )
functionnot yet known, postulated to participate in iron transport
interaction 
receptorfor colicins IA and IB
regulationinduction: by iron and by cAMP/cAMP-receptor protein complex
MW73895 Da; 663 aa



b1451ENTREZ AAC74533
functionputative outer membrane receptor for iron transport
interaction 
regulation 
MW77261 Da; 700 aa


80 - 90 kDa


Outer membrane receptor for FeIII-coprogen, FeIII-ferrioxamine B and FeIII-rhodotorulic acid (fhuE )
functionrequired for the uptake of ironIII via coprogen, ferrioxamine B and rhodotorulic acid
interaction 
receptorfor ferric-rhodotorulic acid
regulationfor induction, the TonB and the ExbB protein have to be active
MW81232 Da; 729 aa


f955ENTREZ AAC73892
functionputative outer membrane receptor for iron transport
interaction 
regulation 
MW81960 Da; 760 aa


Ferrienterobactin receptor precursor (fepA )
functioninvolved in the initial step in iron uptake by binding ferrienterobactin
interaction 
receptorsfor colicins B and D
regulation 
 monomer
3d-structure
spans the membrane 22 times
MW82107 Da; 746 aa


Ferrichrome-iron receptor precursor (fhuA )
functionbinds the ferrichrome-iron ligand
interactionwith TonB
binding of bacteriophage T5 triggers the opening of a high conductance ion channel
receptorfor bacteriophages T5, T1, PHI80 and for colicin M
regulation 
 monomer
3d-structure
spans the membrane 22 times
MW82182 Da; 747 aa


IronIII dicitrate transport protein FecA precursor (fecA )
function 
receptorfor ironIII dicitrate
interactionfor induction TonB and ExbB have to be active
regulationby the iron level mediated by the Fur protein
MW85321 Da; 774 aa


Hypothetical outer membrane usher protein in gltF-nanT intergenic region precursor (yhcD )
functioncould be involved in the export and assembly of a fimbrial subunit across the outer membrane
interaction 
regulation 
MW86289 Da; 793 aa


Organic Solvents Tolerance Protein precursor (ostA )
functiondetermines n-hexane tolerance, involved in OM permeability
interaction 
regulation 
MW89671 Da; 784 aa



90 - 100 kDa


Outer membrane usher protein CssD precursor (Csd2) (cssD )
functioninvolved in the export and assembly of C6 fimbrial subunits across the outer membrane
interaction 
regulation 
MW90393 Da; 802 aa


Unknown protein/Surface antigen D15 family (yaeT )
function 
interaction 
regulation 
  
MW90552; 810 aa


yqiG ENTREZ AAC76082
functionputative outer membrane protein
interaction 
regulation 
MW90553 Da; 821 aa


Hypothetical outer membrane usher protein in nei-gltA intergenic region precursor (ybgQ )
functioncould be involved in the export and assembly of the putative YbgD fimbrial subunit across the outer membrane
interaction 
regulation 
MW90443 Da; 818 aa


Outer membrane usher protein PapC (papC )
functioninvolved in the export and assembly of PapA fimbrial subunits across the outer membrane
appears to form a channel in the outer membrane through wich pilin subunits are transported to the surface
interaction 
regulation 
MW91076 Da; 836 aa


Hypothetical 91.2 kD Protein in rplY-narP intergenic region precursor (yejO )
function 
interaction 
regulation 
MW91202 Da; 863 aa


Hypothetical outer membrane usher protein in ribB-glgS intergenic region precursor (yqiG )
functioncould be involved in the export and assembly of a fimbrial subunit across the outer membrane
interaction 
regulation 
MW91886 Da; 821 aa


Hypothetical 92.2 kD Protein in phoH-csgG intergenic region precursor (ycdS )
function 
interaction 
regulation 
MW92207 Da; 807 aa


Hypothetical outer membrane usher protein in gatY-mrp intergenic region precursor (yehB )
functioncould be involved in the export and assembly of a fimbrial subunit across the outer membrane
interaction 
regulation 
MW92282 Da; 826 aa


Outer membrane usher protein CssD precursor (Csd1) (cssD )
functioninvolved in the export and assembly of C6 fimbrial subunits across the outer membrane
interaction 
regulation 
MW92378 Da; 819 aa


Outer membrane usher protein FasD precursor (fasD )
functioninvolved in the export and assembly of 987P fimbrial subunits across the outer membrane
interaction 
regulation 
MW92354 Da; 835 aa


Hypothetical outer membrane usher protein in agaL-mtr intergenic region precursor (yraJ )
functioncould be involved in the export and assembly of the putative YraH fimbrial subunit across the outer membrane
interaction 
regulation 
MW93616 Da; 838 aa


Hypothetical outer membrane usher protein in pepN-pyrD intergenic region precursor (ycbS )
functioncould be involved in the export and assembly of the putative YcbQ fimbrial subunit across the outer membrane
interaction 
regulation 
MW95241 Da; 866 aa


Outer membrane usher protein HtrE precursor (htrE )
functionprobable porin-like protein necessary for the assembly of a pilin-like protein
interaction 
regulationinduced by heat shock
MW95499 Da; 865 aa


Outer membrane usher protein SfmD precursor (sfmD )
functioninvolved in the export and assembly of SfmA fimbrial subunits across the outer membrane
interaction 
regulation 
MW95677 Da; 867 aa


Outer membrane usher protein FocD (focD )
functioninvolved in the export and assembly of F1C fimbrial subunits across the outer membrane
interaction 
regulation 
MW96210 Da; 875 aa


Outer membrane usher protein FimD precursor (fimD )
functioninvolved in the export and assembly of FimA fimbrial subunits across the outer membrane
interaction 
regulation 
MW96482 Da; 878 aa


Hypothetical outer membrane usher protein in aroC-fadL intergenic region precursor (yfcU )
functioncould be involved in the export and assembly of a fimbrial subunit across the outer membrane
interaction 
regulation 
 97437 Da; 881 aa



f955ENTREZ AAC74286
functionputative adhesion and penetration protein
interaction 
regulation 
MW99685 Da; 955 aa


Above 100 kDa


Intimin (Eae2) (eaeA )
functionnecessary for the production of attaching and effacing lesions on tissue culture cells, believed to mediate adherence
interaction 
regulation 
MW102014 Da; 934 aa


Intimin (Eae1) (eaeA )
functionnecessary for the production of attaching and effacing lesions on tissue culture cells, believed to mediate adherence
interaction 
regulation 
MW102410 Da; 939 aa


Antigen 43 precursor (flu )
functioncontrols colony form variation and autoaggregation
interaction 
regulation 
 outer membrane associated BR>consists of two subunits (alpha and beta)
MW106841 Da; 1039 aa


Bacteriophage N4 adsorption protein A precursor (nrfA )
functionrequired for bacteriophage N4 adsorption, serves as phage receptor
interaction 
regulation 
MW111307 Da; 990 aa


fluENTREZ AAC75061
functionouter membrane fluffing protein, similar to adhesin
interaction 
regulation 
MW112778 Da; 1091 aa


Hypothetical 98.4 kD Protein in alpA-gabD intergenic region precursor (ypjA )
function 
interaction 
regulation 
MW162774 Da; 1569 aa