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ecce/ proteins of the inner membrane/ cell cycle

Cell Division
Proteins Involved in Cell Wall Formation
Proteins for LPS Synthesis
Proteins Determining Cell Shape



Cell Division

Acriflavin resistance protein F (EnvD Protein) (acrF )
functioninvolved in cell envelope formation, is produced in extremely low amounts
interaction 
regulation 
topologytransmembrane domains: 12 (potential)

TMHMM gives 11-33 337-359 366-388 392-414 438-460 470-492 540-562 869-891 896-918 923-945 974-996 1006-1028
SP gives 10-28 340-359 366-385 392-413 442-460 474-496 538-556 872-891 898-917 924-945 974-992 1006-1028

manffirrpi FAWVLAIILM MAGALAILQL PVAqyptiap pavsvsanyp
gadaqtvqdt vtqvieqnmn gidnlmymss tsdsagsvti tltfqsgtdp
diaqvqvqnk lqlatpllpq evqqqgisve kssssylmva gfvsdnpgtt
qddisdyvas nvkdtlsrln gvgdvqlfga qyamriwlda dllnkykltp 200
vdvinqlkvq ndqiaagqlg gtpalpgqql nasiiaqtrf knpeefgkvt
lrvnsdgsvv rlkdvarvel ggenynviar ingkpaaglg iklatganal
dtakaikakl aelqpffpqg mkvlypydtt pfvqlsIHEV VKTLFEAIML
VFLVMYLFLq nmratLIPTI AVPVVLLGTF AILAAFGYsi nTLTMFGMVL 400
AIGLLVDDAI VVVEnvervm medklppkea teksmsqIQG ALVGIAMVLS
AVFIPMAFFG gstgaiyrqF SITIVSAMAL SVLVALILTP ALcatllkpv
saehhenkgg ffgwfnttfd hsvnhytnsv gkilgstgrY LLIYALIVAG
MVVLFLRLPS SFlpeedqgv fltmiqlpag atqertqkvl dqvtdyylkn 600
ekanvesvft vngfsfsgqa qnagmafvsl kpweerngde nsaeavihra
kmelgkirdg fvipfnmpai velgtatgfd felidqaglg hdaltqarnq
llgmaaqhpa slvsvrpngl edtaqfklev dqekaqalgv slsdinqtis
talggtyvnd fidrgrvkkl yvqadakfrm lpedvdklyv rsangemvpf 800
safttshwvy gsprleryng lpsmeiqgea apgtssgdam almenlaskl
pagigydwtg msyqerlsGN QAPALVAISF VVVFLCLAAL YeswsIPVSV
MLVVPLGIVG VLLAATLFnq knDVYFMVGL LTTIGLSAKN AILIVefakd
lmekegkgvv eatlmavrmr lrpILMTSLA FILGVLPLAI SNGAGSgaqn 1000
avgigVMGGM VSATLLAIFF VPVFFVVIrr cfkg

MW111454 Da; 1034 aa


Cell division protein FtsK (ftsK )
functionrequired for septum formation, may be involved in peptidoglycan synthesis or modification
interaction 
regulation 
topologytransmembrane domains: 5 (potential), SP has 6

TMHMM gives 22-44 75-97 110-132 137-158 165-187
SP gives 22-42 76-96 112-132 166-186 309-329 560-580

msqeyiedke vtltklssgr rLLEALLILI VLFAVWLMAA LLSFnpsdps
wsqtawhepi hnlggmpgaw ladtLFFIFG VMAYTIPVII VGGCWFAwrh
qssdeyidyF AVSLRIIGVL ALILTSCGLA AInaddIWYF ASGGVIGSLL
STTLQPLLhs sggtIALLCV WAAGLTLFTG WSWVTIAekl ggwilniltf 200
asnrtrrddt wvdedeyedd eeyedenhgk qhesrraril rgalarrkrl
aekfinpmgr qtdaalfsgk rmdddeeity targvaadpd dvlfsgnrat
qpeydeydpl lngapitepv avaaaattat qswaapvepv tqtppvasvd
vppaqptvaw qpvpgpqtge pviapapegy pqqsqyaqpa vqyneplqqp 400
vqpqqpyyap aaeqpaqqpy yapapeqpva gnawqaeeqq stfapqstyq
teqtyqqpaa qeplyqqpqp veqqpvvepe pvveetkpar pplyyfeeve
ekrarereql aawyqpipep vkepepikss lkapsvaavp pveaaaavsp
lasgvkkatl atgaaatvaa pvfslansgg prpqvkegig pqlprpkrir 600
vptrrelasy giklpsqraa eekareaqrn qydsgdqynd deidamqqde
larqfaqtqq qrygeqyqhd vpvnaedada aaeaelarqf aqtqqqrysg
eqpaganpfs lddfefspmk allddgphep lftpivepvq qpqqpvapqq
qyqqpqqpvp pqpqyqqpqq pvapqpqyqq pqqpvapqqq yqqpqqpvap 800
qqqyqqpqqp vapqpqdtll hpllmrngds rplhkpttpl psldlltppp
sevepvdtfa leqmarlvea rladfrikad vvnyspgpvi trfelnlapg
vkaarisnls rdlarslstv avrvvevipg kpyvglelpn kkrqtvylre
vldnakfrdn pspltvvlgk diagepvvad lakmphllva gttgsgksvg 1000
vnamilsmly kaqpedvrfi midpkmlels vyegiphllt evvtdmkdaa
nalrwcvnem erryklmsal gvrnlagyne kiaeadrmmr pipdpywkpg
dsmdaqhpvl kkepyivvlv defadlmmtv gkkveeliar laqkaraagi
hlvlatqrps vdvitglika niptriaftv sskidsrtil dqagaesllg 1200
mgdmlysgpn stlpvrvhga fvrdqevhav vqdwkargrp qyvdgitsds
eseggaggfd gaeeldplfd qavqfvtekr kasisgvqrq frigynraar
iieqmeaqgi vseqghngnr evlapppfd

MW146662 Da; 1329 aa


Cell division protein FtsL (ftsL )
functioninvolved in cell division and cell growth, may play some role in coupling cell division and peptidoglycan physiology
interaction 
regulation 
topologytransmembrane domains: 1 (potential)

TMHMM gives 35-57
SP gives 38-57

misrvteals kvkgsmgshe rhalpgvigd dllrFGKLPL CLFICIILTA
VTVVTTAhht rlltaqreql vlerdaldie wrnlileena lgdhsrveri
ateklqmqhv dpsqenivvq k

MW13627 Da; 121 aa


Cell division protein FtsN (ftsN )
functionessential for cell division, may play a role in the assembly or stability of the septation machinery
interactionmay interact with FtsA, Pbp3 and FtsQ
regulation 
topologytransmembrane domains: 1 (potential)

TMHMM gives 29-51
SP gives 29-55

maqrdyvrrs qpapsrrkks tsrkkqrnVP AVSPAMVAIA AAVLVTFIGG
Lyfithhkke esetlqsqkv tgnglppkpe erwryikele srqpgvrapt
epsaggevkt peqltpeqrq lleqmqadmr qqptqlvevp wneqtpeqrq
qtlqrqrqaq qlaeqqrlaq qsrtteqswq qqtrtsqaap vqaqprqskp 200
assqqpyqdl lqtpahttaq skpqqaapva raadapkpta ekkderrwmv
qcgsfrgaeq aetvraqlaf egfdskittn ngwnrvvigp vkgkenadst
lnrlkmaght ncirlaagg

MW35779 Da; 319 aa


Cell division protein FtsQ (ftsQ )
functionmay be involved in anomalous filament growth
interactionmay interact with FtsZ, FtsA and Pbp3
regulation 
topologytransmembrane domains: 1 (potential)

TMHMM gives 25-47
SP gives 25-49

msqaalntrn seeevssrrn ngtrLAGILF LLTVLTTVLV SGWVVLGWme
daqrlplskl vltgerhytr nddirqsila lgepgtfmtq dvniiqtqie
qrlpwikqvs vrkqwpdelk ihlveyvpia rwndqhmvda egntfsvppe
rtskqvlpml ygpegsanev lqgyremgqm lakdrftlke aamtarrswq 200
ltlnndikln lgrgdtmkrl arfvelypvl qqqaqtdgkr isyvdlryds
gaavgwaplp peestqqqnq aqaeqq

MW31434 Da; 276 aa


Cell division protein FtsW (ftsW )
functionseptum-peptidoglycan biosynthetic protein involved in cell wall formation, plays a role in the stabilization of the FtsZ ring during cell division
interaction 
regulation 
topologytransmembrane domains: 10 (potential), SP has 9

TMHMM gives 13-32 47-66 86-105 110-132 175-194 198-217 222-244 307-329 341-363 373-395
SP gives 13-33 48-68 87-107 112-132 185-205 219-239 302-322 343-363 374-394

mrlslprlkm prLPGFSILV WISTALKGWV MGsrekdtds limydrTLLW
LTFGLAAIGF IMVTSAsmpi gqrltndpff fakrdGVYLI LAFILAIITL
RLPMEfwqrY SATMLLGSII LLMIVLVVGS SVkgasrwid lgllriqpae
ltklslfcyi anylvrkgde vrnnLRGFLK PMGVILVLAV LLLAqpdLGT 200
VVVLFVTTLA MLFLAGAklw qFIAIIGMGI SAVVLLILAE PYRIrrvtaf
wnpwedpfgs gyqltqslma fgrgelwgqg lgnsvqkley lpeahtdfif
aiigeeLGYV GVVLALLMVF FVAFRAMSIg rkaleidhrf SGFLACSIGI
WFSFQALVNV GAAagmlptk glTLPLISYG GSSLLIMSTA IMMLLridye 400
trlekaqafv rgsr

MW45987 Da; 414 aa


IspZ (ispZ/yciB )
functioninvolved in cell division; probably involved in intracellular septation
interaction 
regulation 
topologytransmembrane domains: 5 (potential)

TMHMM gives 22-44 51-68 78-95 119-141 151-170
SP gives 23-43 47-67 84-105 118-140 145-164

mkqfldflpl vvffafykiy dIYAATAALI VATAIVLIYS WVrfrkvekm
ALITFVLVVV FGGLTLFFhn defikwkVTV IYALFAGALL VSQWVmkkpl
iqrmlgkelt lpqpvwskln LAWAVFFILC GLANIYIAFW Lpqniwvnfk
VFGLTALTLI FTLLSGIYIY rhmpqedks

MW20790 Da; 179 aa


Cell division protein ZipA (zipA )
functionprobable receptor of the septal ring structure, may anchor it to the inner membrane
interactioninteracts directly with the cell division protein FtsZ
regulation 
topologytransmembrane domains: 1 (potential)

TMHMM gives 5-27
SP gives 7-27

mmqdlrLILI IVGAIAIIAL LVHGFWTSrk erssmfrdrp lkrmkskrdd
dsydedvedd egvgevrvhr vnhapanaqe heaarpspqh qyqppyasaq
prqpvqqppe aqvppqhaph paqpvqqpay qpqpeqplqq pvspqvapap
qpvhsapqpa qqafqpaepv aapqpepvae papvmdkpkr keaviimnva 200
ahhgselnge allnsiqqag fifgdmniyh rhlspdgsgp alfslanmvk
pgtfdpemkd fttpgvtifm qvpsygdelq nfklmlqsaq hiadevggvv
lddqrrmmtp qklreyqdii revkdana

MW36433 Da; 328 aa


Cell Wall Formation

Penicillin-binding protein 3 (ftsI )
functioncell wall formation, essential for formation of septum of the murein sacculus, final stages in peptidoglycan synthesis, bulk of the protein, except for the N-terminal anchor protrudes into periplasm space.
multifunctional enzyme
has a N-terminal penicillin-insensitive transglycosylase domain, and a C-terminal penicillin-sensitive transpeptidase domain
interaction 
regulation 
topologytransmembrane domains: 1 (potential)

TMHMM gives 21-43
SP gives 19-39

mkaaaktqkp krqeehanfi swrFALLCGC ILLALAFLLG RVAWLqvisp
dmlvkegdmr slrvqqvsts rgmitdrsgr plavsvpvka iwadpkevhd
aggisvgdrw kalanalnip ldqlsarina npkgrfiyla rqvnpdmady
ikklklpgih lreesrryyp sgevtahlig ftnvdsqgie gveksfdkwl 200
tgqpgerivr kdrygrvied isstdsqaah nlalsiderl qalvyrelnn
avafnkaesg savlvdvntg evlamansps ynpnnlsgtp keamrnrtit
dvfepgstvk pmvvmtalqr gvvrensvln tipyringhe ikdvarysel
tltgvlqkss nvgvsklala mpssalvdty srfglgkatn lglvgersgl 400
ypqkqrwsdi eratfsfgyg lmvtplqlar vyatigsygi yrplsitkvd
ppvpgervfp esivrtvvhm mesvalpggg gvkaaikgyr iaiktgtakk
vgpdgryink yiaytagvap asqprfalvv vindpqagky yggavsapvf
gaimggvlrt mniepdaltt gdknefvinq gegtggrs

MW63877 Da; 588 aa


Penicillin-binding protein 1A (mrcA )
functioncell wall formation, synthesis of cross-linked peptidoglycan from the lipid intermediates, final stages in peptidoglycan synthesis
multifunctional enzyme
has a penicillin-insensitive transglycosylase domain, and a penicillin-sensitive transpeptidase domain
interaction 
regulation 
 transmembrane domains: 1 (potential)

TMHMM gives 7-29
SP gives 2-26

mkfvkYFLILAVCCILLGAGSIYGLYryiepqlpdvatlkdvrlqipmqi
ysadgeliaqygekrripvtldqippemvkafiatedsrfyehhgvdpvg
ifraasvalfsghasqgastitqqlarnfflspertlmrkikevflairi
eqlltkdeilelylnkiylgyraygvgaaaqvyfgktvdqltlnemavia
glpkapstfnplysmdravarrnvvlsrmldegyitqqqfdqtrteaina
nyhapeiafsapylsemvrqemynrygesayedgyriyttitrkvqqaaq
qavrnnvldydmrhgyrgpanvlwkvgesawdnnkitdtlkalptygpll
paavtsanpqqatamladgstvalsmegvrwarpyrsdtqqgptprkvtd
vlqtgqqiwvrqvgdawwlaqvpevnsalvsinpqngavmalvggfdfnq
skfnratqalrqvgsnikpflytaamdkgltlasmlndvpisrwdasags
dwqpknsppqyagpirlrqglgqsknvvmvramramgvdyaaeylqrfgf
paqnivhteslalgsasftpmqvargyavmanggflvdpwfiskiendqg
gvifeakpkvacpecdipviygdtqksnvlenndvedvaisreqqnvsvp
mpqleqanqalvaktgaqeyaphvintplafliksalntnifgepgwqgt
gwragrdlqrrdiggktgttnsskdawfsgygpgvvtsvwigfddhrrnl
ghttasgaikdqisgyeggaksaqpawdaymkavlegvpeqpltpppgiv
tvnidrstgqlanggnsreeyfiegtqptqqavhevgttiidngeaqelf

MW93636 Da; 850 aa


Penicillin-binding protein 1B (mrcB )
functioncell wall formation, synthesis of cross-linked peptidoglycan from the lipid intermediates, final stages in peptidoglycan synthesis
multifunctional enzyme
has a penicillin-insensitive transglycosylase domain, and a penicillin-sensitive transpeptidase domain
interaction 
regulation 
 transmembrane domains: 1 (potential)

TMHMM gives 65-87
SP gives 64-87

magndrepig rkgkptrpvk qkvsrrryed dddyddyddy edeepmprkg
kgkgkgrkpr gkrgWLWLLL KLAIVFAVLI AIYGVYLdqk irsridgkvw
qlaaavygrm vnlepdmtis knemvkllea tqyrqvskmt rpgeftvqan
siemirrpfd fpdskegqvr arltfdgdhl ativnmennr qfgffrldpr 200
litmisspng eqrlfvprsg fpdllvdtll atedrhfyeh dgislysigr
avlanltagr tvqgastltq qlvknlflss ersywrkane aymalimdar
yskdrilely mnevylgqsg dneirgfpla slyyfgrpve elsldqqall
vgmvkgasiy npwrnpklal errnlvlrll qqqqiidqel ydmlsarplg 400
vqprggvisp qpafmqlvrq elqaklgdkv kdlsgvkift tfdsvaqdaa
ekaavegipa lkkqrklsdl etaivvvdrf sgevramvgg sepqfagynr
amqarrsigs lakpatylta lsqpkiyrln twiadapial rqpngqvwsp
qnddrryses grvmlvdalt rsmnvptvnl gmalglpavt etwiklgvpk 600
dqlhpvpaml lgalnltpie vaqafqtias ggnraplsal rsviaedgkv
lyqsfpqaer avpaqaaylt lwtmqqvvqr gtgrqlgaky pnlhlagktg
ttnnnvdtwf agidgstvti twvgrdnnqp tklygasgam siyqrylanq
tptplnlvpp ediadmgvdy dgnfvcsggm rilpvwtsdp qslcqqsemq 800
qqpsgnpfdq ssqpqqqpqq qpaqqeqkds dgvagwikdm fgsn

MW94266 Da; 844 aa


Periplasmic glucans biosynthetic protein MdoH (mdoH )
functioninvolved in the biosynthesis of periplasmic membrane-derived oligosaccharides (MDO), necessary for normal glycosyl transferase activity
could be a glucosyl transferase or simply a subunit of this enzyme
interaction 
regulation 
topologytransmembrane domains: 6 (potential), SP has 8

TMHMM gives 139-156 194-216 512-534 568-590 603-625 680-702
SP gives 140-160 194-214 426-446 513-533 570-590 615-635 680-700 746-766

mnktteyida mpiaasekaa lpktdiravh qaldaehrtw areddspqgs
vkarleqawp dsladgqlik ddegrdqlka mpeakrssmf pdpwrtnpvg
rfwdrlrgrd vtprylarlt keeqeseqkw rtvgtirrYI LLILTLAQTV
VATWYMktil pyqgwalinp mdmvgqdlwv sfmqllpyml qtgILILFAV 200
LFCWVSAGFW TALMGFlqll igrdkysisa stvgdeplnp ehrtalimpi
cnedvnrvfa glratwesvk atgnakhfdv yilsdsynpd icvaeqkawm
eliaevggeg qifyrrrrrr vkrksgnidd fcrrwgsqys ymvvldadsv
mtgdclcglv rlmeanpnag iiqsspkasg mdtlyarcqq fatrvygplf 400
taglhfwqlg eshywghnai irvkpfiehc alaplpgegs fagsilshdf
veaalmrrag wgvwiaydlp gsyeelppnl ldelkrdrrw chgnlmnfrl
flvkgmhpvh rAVFLTGVMS YLSAPLWFMF LALStalqvv haltepqyfl
qprqlfpvwp qwrpelaIAL FASTMVLLFL PKLLSILLIW ckgtkeyggf 600
wrVTLSLLLE VLFSVLLAPV RMLFHtvfvv saflgwevvw nspqrdddst
swgeafkrhg sqlllglvwa vgmawldlrF LFWLAPIVFS LILSPFVSVI
SSratvglrt krwklflipe eysppqvlvd tdrflemnrq rslddgfmha
vfnpsfnala tamatarhra skvleiardr hveqalnetp eklnrdrrlv 800
llsdpvtmar lhfrvwnspe rysswvsyye giklnplalr kpdaasq

MW96937 Da; 847 aa


Penicillin-binding protein 2 (mrdA )
functioncell wall formation: final stages in peptidoglycan synthesis, determination of rod shape of cell
multifunctional
has a penicillin-insensitive transglycosylase domain, and a penicillin-sensitive transpeptidase domain
interaction 
regulation 
topologytransmembrane domains: 1 (potential), SP has )

TMHMM gives 21-43

mklqnsfrdytaesalfvrrALVAFLGILLLTGVLIANLYNLQIVrftdy
qtrsnenriklvpiapsrgiiydrngiplalnrtiyqiemmpekvdnvqq
tldalrsvvdltdddiaafrkerarshrftsipvktnltevqvarfavnq
yrfpgvevkgykrryypygsalthvigyvskindkdverlnndgklanya
athdigklgieryyedvlhgqtgyeevevnnrgrvirqlkevppqaghdi
yltldlklqqyietllagsraavvvtdprtggvlalvstpsydpnlfvdg
isskdysallndpntplvnratqgvyppastvkpyvavsalsagvitrnt
tlfdpgwwqlpgsekryrdwkkwghgrlnvtrsleesadtffyqvaydmg
idrlsewmgkfgyghytgidlaeersgnmptrewkqkrfkkpwyqgdtip
vgigqgywtatpiqmskalmilindgivkvphllmstaedgkqvpwvqph
eppvgdihsgywelakdgmygvanrpngtahkyfasapykiaaksgtaqv
fglkanetynahkiaerlrdhklmtafapynnpqvavamilenggagpav
gtlmrqildhimlgdnntdlpaenpavaaaedh

MW70856 Da; 633 aa


LPS Synthesis

O-antigen polymerase (rfc )
functionmay link O-antigen tetrasaccharides into long chains, giving rise to the typical smooth LPS
interaction 
regulation 
topologytransmembrane domains: 12 (potential), SP has 9

TMHMM gives 2-19 23-42 55-77 97-119 140-162 177-206 213-232 237-259 272-289 309-331 338-355 365-382
SP gives 23-43 57-77 97-117 143-163 180-200 215-235 312-332 338-358 361-381

mIYLVISVFL ITAFICLYLk kdIFYPAVCV NIIFALVLLG YEitsdiyaf
qlndATLIFL LCNVLTFTLS CLLTESVldl nirkvnnaiy sipskkVHNV
GLLVISFSMI YICMRLSNYq fgtsllsymn lirdadvedT SRNFSAYMQP
IILTTFALFI WSkkftntkv sktftlLVFI VFIFAIILNT GKQIVFMVII 200
SYAFIVgvnr vkHYVYLITA VGVLFSLYML FLrglpGGMA YYLSMYLVSP
IIAFQEFYFq qvsnsasshv fWFFERLMGL LTGGVSMSLh kefvwvglpt
nvytafsdYV YISAELSYLM MVIHGCISGV LwrlsrnYIS VKIFYSYFIY
TFSFIfyhes fmtnISSWIQ ITLCIIVFSQ FLkaqkik

MW44744 Da; 388 aa


Chain length determinant protein (WZB1) (wzzB )
functionconfers a modal distribution of chain length on the O-antigen component of the LPS
interaction 
regulation 
 transmembrane domains: 2 (potential)

TMHMM gives 32-51 297-316
SP gives 32-52 296-316

mrvennnvsg qnhdpeqidl idllvqlwrg kMTIIISVIV AIALAIGYLA
Vakekwtsta iitqpdvgqi agynnamnvi ygqaapkvsd lqetligrfs
safsalaetl dnqeereklt iepsvknqql pltvsyvgqt aegaqmklaq
yiqqvddkvn qelekdlkdn ialgrknlqd slrtqevvaq eqkdlrirqi 200
qealqyanqa qvtkpqiqqt geditqdtlf llgsealesm ikheatrplv
fspnyyqtrq nlldieslkv ddldihayry vmkpmlpirr dspkkaITLI
LAVLLGGMVG AGIVLGrnal rnynak

MW36455 Da; 326 aa


Chain length determinant protein (WZB2) (wzzB )
functionconfers a modal distribution of chain length on the O-antigen component of the LPS
interaction 
regulation 
 transmembrane domains: 2 (potential)

TMHMM gives 32-51 296-315
SP gives 32-52 295-315

msisdnnmsg rshdpeqidl idllmqlwrg kVTIIICIVV AIALAVGYLA
Vakekwtsia ivtqpdagql asynnamdvl fganapemtd vqagfigrfs
safsalaetl dnqqepekls idaavkgqtl plkvsytgkt seeaqktlaq
yiqqvdegva kelnadlsms metrladlqk slaaqeavak eqktlriaqm 200
tqalkvaqqs niklpqvqqv dqvsqdsmfm lgsealssmv eneatrpltf
sdqyyqtrqn llevqaleva pdsvhayryv mkptlpirrd spkkaITLVL
AVLIGGMIGA GVVLGrnalr gykakae

MW35652 Da; 327 aa


Chain length determinant protein (WZB3) (wzzB )
functionconfers a modal distribution of chain length on the O-antigen component of the LPS
interaction 
regulation 
 transmembrane domains: 2 (potential)

TMHMM gives 32-51 296-315
SP gives 32-52 295-315

mrvennnvsg qnhdpeqidl idllvqlwrg kMTIIISVIV AIALAIGYLA
Vakekwtsta iitqpdvgqi agynnamnvi ygqaapkvsd lqetligrfs
safsalaetl dnqeepeklt iepsvknqql pltvsyvgqt aegaqmklaq
yiqqvddkvn qelekdlkdn ialgrknlqd slrtqevvaq eqkdlrirqi 200
qealqyanqa qvtkpqiqqt qdvtqdtmfl lgsealesmi kheatrplvf
ssnyyqtrqn lldidnldvd kldihayryv mkptlpirrd spkkaITLIL
AVLLGGMVGA GIVLGrnalr nynak

MW36314 Da; 325 aa


Chain length determinant protein (WZB8) (wzzB )
functionconfers a modal distribution of chain length on the O-antigen component of the LPS
interaction 
regulation 
 transmembrane domains: 2 (potential)

TMHMM gives 32-51 296-315
SP gives 32-52 295-315

mrvennnvsg qnldpeqidl idllvqlwrg kMTIIISVIV AIVLAIGYLV
Vakekwtsta ivtqpdvgqi agynnainvi ygsaapkvse iqsiligrfs
ttfsalaetl dnqeepeklt ieptvknqsl plavsyvgqs peaaqkqlaq
yiqqvddqvn delekdlkdn ialrmknlqd slktqevvaq eqkelrirqi 200
qealqyanqa qvtkpqiqqt qdvtqdtmfl lgsdalesmv kheasrplvf
sstyyqtrqn lldieslkvd dldihayryv mkptlpirrd spkkaITLIL
AVLLGGMVGA GIVLGrnalr nynak

MW36246 Da; 325 aa


Lipopolysaccharide biosynthesis protein WzxC (wzxC )
functionprobable export protein
interaction 
regulation 
topologytransmembrane domains: 12 (potential)

TMHMM gives 13-35 45-67 80-102 165-187 199-218 233-255 284-306 326-348 355-377 381-403 416-438 448-467
SP gives 13-33 43-63 82-102 105-125 158-178 237-257 289-309 323-343 365-385 387-407 418-438 446-466

mslrektisg akWSAIATVI IIGLGLVQMT VLARIidnhq fgllTVSLVI
IALADTLSDF GIANSIIqrk eishlelttL YWLNVGLGIV VCVAVFLLSD
LIgdvlnnpd lapliktlsl afvviphgqq fralmqkele fnkigmiets
avlagftctv vsahFWPLAM TAILGYLVNS AVRTLLFgyf grkiyrpgLH 200
FSLASVAPNL RFGAWLTAds iinylntnls tlVLARILGA GVAGGYNLAY
NVAVVppmkl npiitrvlfp afakiqddte klrVNFYKLL SVVGIINFPA
LLGLMVvsnn fvplvfgekw nsiipVLQLL CVVGLLRSVG NPIGSLLMak
arvdISFKFN VFKTFLFIPA IVIGGQMaga IGVTLGFLLV QIINTILSYF 400
VMIkpvlgss yrqyiLSLWL PFYLSLPTLV VSYALGIVlk gqlalgmLLA
VQIATGVLAF VVMIVLSrhp lvvevkrqfc rsekmkmllr ag

MW53692 Da; 429 aa


Lipopolysaccharide biosynthesis protein WzzE (wzzE )
function 
interaction 
regulation 
topologytransmembrane domains: 2 (potential)

TMHMM gives 30-52 324-343
SP gives 32-52 324-344

mmtqpmpgkp aedaeneldi rglfrtlwaG KLWIIGMGLA FALIALAYTF
FArqewssta itdrptvnml ggyysqqqfl rnldvrsnma sadqpsvmde
aykefvmqla swdtrrefwl qtdyykqrmv gnskadaall deminniqfi
pgdftravnd svkliaetap dannllrqyv afasqraash lndelkgawa 200
artiqmkaqv krqeevakai ydrrmnsieq alkiaeqhni srsatdvpae
elpdsemfll grpmlqarle nlqavgpafd ldydqnraml ntlnvgptld
prfqtyrylr tpeepvkrds prrAFLMIMW GIVGGLIGAG VALtrrcsk

MW39620 Da; 349 aa


Cell Shape Determining Proteins

Rod shape determining protein MreC (mreC )
functioninvolved in the formation of rod shape, may contribute to regulation of formation of the penicillin-binding proteins
interaction 
regulation 
topologytransmembrane domains: probably 0
MW39530 Da; 367 aa


Rod shape determining protein MreD (mreD )
functioninvolved in the formation of rod shape, may contribute to regulation of formation of the penicillin-binding proteins
interaction 
regulation 
topologytransmembrane domains: 5 (potential)

TMHMM gives 10-24 31-53 68-90 97-119 134-151
SP gives 10-30 31-51 56-76 106-126 132-152

masyrsqgrW VIWLSFLIAL LLQImpwpdn LIVFRPNWVL LILLYWILAL
PHRvnvgtgf vmgaildLIS GSTLGVRVLA MSIIAYLVAL kyqlfrNLAL
WQQALVVMLL SLVVDIIVFw aeflvinvsf rpeVFWSSVV NGVLWPWIFL
Lmrkvrqqfa vq

MW18788 Da; 162 aa


Rod shape-determining protein RodA (rodA )
functionresponsible for the rod shape of cell, required for the expression of the enzymatic activity of PBP2
interaction 
regulation 
topologytransmembrane domains: 9 (potential)

TMHMM gives 15-37 50-67 77-99 136-155 160-179 181-203 272-294 306-328 338-360
SP gives 20-40 50-70 75-95 136-156 160-180 183-203 263-283 312-332 336-356

mtdnpnkktf wdkvHLDPTM LLILLALLVY SALVIWSasg qdigmmerkI
GQIAMGLVIM VVMAQIPprv yegwapYLYI ICIILLVAVD AFGAISKGAq
rwldlgivrf qpseiakiav plmvarfinr dvcppSLKNT GIALVLIFMP
TLLVAaqpdL GTSILVALSG LFVLFLSGLs WRLIGVAVVL VAAFIPILWF 200
FLMhdyqrqr vmmlldpesd plgagyhiiq skiaigsggl rgkgwlhgtq
sqleflperh tdfifavlae eLGLVGILIL LALYILLIMR GLWIaaraqt
tfgrvMAGGL MLILFVYVFV NIGMVSGIlp vvgvpLPLVS YGGSALIVLM
AGFGIVMsih thrkmlsksv

MW40476 Da; 370 aa