List of Point Mutations in TM of MalF
malF - allele Mutation in TM 3
369 Y69H
372 M72L
373 A73G
3732 A73V
375 M75T
376 G76R
382 P82S
385 C85S
391 F91Y
3912 F91C


malF - allele Mutation in TM 4
415 F277I
482 I280F
447 F281S
472 V282D
473 W283R
42 F293I
410 T295M
446 G299C
4304 C304L
453 Q307R


malF - allele Mutation in TM 5
54 L321R
5431 L321W
54517 L323Q
5215 P324H
5165 Y325S
538 P328L
594 S329L


malF - allele Mutation in TM 6
647 M371I
616 L372R
651 I374T
64 N376K
641 N376H
652 N376T
611 W378R
6190 L379Q
623 G380D
615 G380C
620 G380S
666 Y383S
621 L387P
66 L387H


malF - allele Mutation in TM 7
7288 L422R
71141 K424Q
724 L426P
741 P428E
72120 L429Q
72100 L429P
765 I431K
7266 S433R
7130 F436L
7123 F436S
714 N439T
7121 L443R
7138 L447stop
7143 L447stop


malF - allele Mutation in TM 8
831 G485V
816 L486P
842 A488P
8033 A491D
843 T492R
846 I494N
860 I494L
84 F495L
811 L496P
62281 L496V
827 L497R
62284 L497Q
853 V498M


The ref. for the mutations in TM 3, 4, and 5 is:

Steinke, A., Grau, S., Davidson A., Hofmann, E., and M Ehrmann 2001. Characterization of transmembrane domains 3, 4, and 5 of MalF by mutational analysis. J. Bacteriol. 183:375-381entrez/medline


The ref. for the mutations in TM 6, 7, and 8 is:

Ehrle R., Pick C., Ulrich R., Hofmann E. and M. Ehrmann. 1996. Characterization of transmembrane domains 6, 7 and 8 of MalF by mutational analysis. J. Bacteriol. 178: 2255-2262. entrez/medline




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