Connective Tissue Biology
Research in the Group centres around musculoskeletal tissues particularly in relation to cell and matrix biology in development, ageing and pathology.
A particular focus is the biology of the synovial joint as an integrated organ of differing tissue types together with surrounding tissues and how these may interact during pathogenesis of degenerative joint diseases.
Members of the Connective Tissue Biology Group are all members of Cardiff Institute of Tissue Engineering and Repair (CITER) a virtual interdisciplinary Institute of over 100 scientists that interact to bring a wide variety of expertise to address the challenges of regenerative medicine and tissue repair in both trauma and disease.
- Professor Charlie Archer
synovial joint biology - Professor Ifor Bowen
cell death - Professor Bruce Caterson
monoclonal antibody technologies to study onset of degenerative joint diseases - Professor Vic Duance
structure and function of the minor collagens of cartilage, cell signalling pathways associated with mechanical and cytokine mediated cartilage degeneration - Dr Catherine Boulter
regulation of stem/progenitor cells in development and disease - Dr Clare Hughes
cartilage proteoglycan metabolism in osteoarthritis
- Dr Alvin Kwan
regulation of chondrocyte maturation during endochondral ossification - Dr Deborah Mason
signalling mechanisms regulating bone and cartilage turnover, in osteoporosis, rheumatoid arthritis and osteoarthritis - Dr Jim Ralphs
cellular control of extracellular matrix secretion and organisation in connective tissues - Dr Daniela Riccardi
molecular mechanisms of nutrient sensing - Prof Geoff Richards
Honorary Professor
Director of AO Research Institute