Dr Florian Siebzehnrubl
Location:European Cancer Stem Cell Research Institute, Cardiff School of Biosciences Hadyn Ellis Building, Maindy Road, Cardiff CF24 4HQ
Glioblastoma is the most common and lethal brain cancer in the adult population, and the recurrence of these cancers post treatment is a particular problem contributing to patient demise. Glioblastomas exhibit a high degree of heterogeneity, both between individual tumours and within the same tumour. This heterogeneity is observable on several levels, ranging from genetic mutations to cellular and histopathological variations. I am broadly interested in the contributions of cellular subpopulations to tumour heterogeneity, progression and recurrence, and how certain transcription factors regulate these processes.