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Dr Karen Reed 


My Researcher ID profile can be found at:

http://www.researcherid.com/rid/B-8813-2011

  • Feng GJ, Cotta W, Wei XQ, Poetz O, Evans R, Jardé T, Reed K, Meniel V, Williams GT, Clarke AR, Dale TC.
    Gastroenterology. 2012 143(6):1650-9

Conditional Disruption of Axin1 Leads to Development of Liver Tumors in Mice.

 

  • Reed KR, Tunster SJ, Young M, Carrico A, John RM, Clarke AR 

Gut. 2011

Entopic over-expression of Ascl2 does not accelerate tumourigenesis in APCmin mice 

 

  • Kant P, Sainsbury A, Reed KR, Pollard SG, Scott N, Clarke AR, Coletta PL, Hull MA. 

Gut. 2011 60(7):893-901

Rectal epithelial cell mitosis and expression of macrophage migration inhibitory factor are increased 3 years after Roux-en-Y gastric bypass (RYGB) for morbid obesity: implications for long-term neoplastic risk following RYGB. 

  • Cole AM, Myant K, Reed KR, Ridgway RA, Athineos D, Van den Brink GR, Muncan V, Clevers H, Clarke AR, Sicinski P, Sansom OJ.

2010 Cancer Res. Oct 5

Cyclin D2-Cyclin-Dependent Kinase 4/6 Is Required for Efficient Proliferation and Tumorigenesis following Apc Loss.

 

  • Burke ZD, Reed KR, Phesse TJ, Sansom OJ, Clarke AR, Tosh D.

2009 Gastroenterology.  136(7):2316-2324

Liver zonation occurs through a beta-catenin-dependent, c-Myc-independent mechanism.

 

  • Karen R Reed, Dimitris Athineos, Valerie S Meniel, Julie A Wilkins, Rachel A Ridgway, Zoé D. Burke, Vanesa Muncan, Alan R Clarke, Owen J  Sansom.

2008 PNAS 105(48):18919-23s

B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of Apc loss in the liver.

 

  • Phesse TJ, Parry L, Reed KR, Ewan KB, Dale TC, Sansom OJ, Clarke AR.

2008 Mol Cell Biol. 28:6094-103

Deficiency of Mbd2 attenuates Wnt signaling.

 

  • Reed KR, Meniel VS, Marsh V, Cole A, Sansom OJ, Clarke AR.

2008. BMC Cancer, 8:162. “Highly accessed article”

A limited role for p53 in modulating the immediate phenotype of Apc loss in the intestine.

 

  • Sansom OJ, Meniel VS, Muncan V, Phesse TJ, Wilkins JA, Reed KR, Vass JK, Athineos D, Clevers H, Clarke AR.

2007. Nature 446:676-9

Myc deletion rescues Apc deficiency in the small intestine.

 

  • Reed KR, Sansom OJ, Hayes AJ, Gescher AJ, Peters JM and Clarke AR.

2006. BMC Cancer, 6:113

PPARdelta status and mismatch repair mediated neoplasia in the mouse intestine..

 

  • Sansom OJ, Griffiths DFR, Reed KR, Winton DJ and Clarke AR.

2005. Oncogene 24:8205-10.

Apc Deficiency Predisposes to Renal Carcinoma in the Mouse.

 

  • Sansom OJ, Reed KR, van de Wetering M, Muncan V, Winton DJ, Clevers H and Clarke AR.

2005.  J Biol. Chem 280:28463-7.

Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine.

 

  • Reed KR, Sansom OJ, Hayes AJ, Gescher AJ, Winton DJ, Peters JM and Clarke AR.

2004. Oncogene 23:8992-6.

PPARdelta status and Apc mediated tumourigenesis in the mouse intestine.

 

  • Sansom OJ, Reed KR, Hayes AJ, Ireland H, Brinkmann H, Newton IP, Batlle E, Simon-Assmann P, Clevers H, Nathke IS, Clarke AR and Winton DJ.

2004. Genes and Development 18: 1385-1390.

Loss of Apc immediately perturbs differentiation and migration in the small intestine.

 

  • Cerrato F, Dean W, Davies K, Kagotani K, Mitsuya K, Okumura K, Riccio A, Reik W. 

2003 Human Molecular Genetics 12(23):3123-32.

Paternal imprints can be established on the maternal Igf2-H19 locus without altering replication timing of DNA.

 

  • Davies K, Bowden L, Smith P, Dean W, Hill D, Furuumi H, Sasaki H, Cattanach B, Reik W.

2002 Development. 129(7):1657-68.

Disruption of mesodermal enhancers for Igf2 in the minute mutant.

 

  • Paulsen M, El-Maarri O, Engemann S, Strodicke M, Franck O, Davies K, Reinhardt R, Reik W, Walter J. 

2000 Human Molecular Genetics 9(12):1829-41.

Sequence conservation and variability of imprinting in the Beckwith-Wiedemann syndrome gene cluster in human and mouse.

 

  • Reik W, Constancia M, Dean W, Davies K, Bowden L, Murrell A, Feil R, Walter J, Kelsey G. 

2000 Int J Dev Biol. 44(1):145-50.

Igf2 imprinting in development and disease.

 

Contributions to compiled volumes

  • Reik W, Davies K, Dean W, Kelsey G, Constancia M. 

2001 Novartis Found Symp.237:19-31; discussion 31-42.

Imprinted genes and the coordination of fetal and postnatal growth in mammals.