Dr Dipak Ramji
Telephone:+44 (0)29 208 76753
Fax:+44 (0)29 208 74116
Location:Cardiff School of Biosciences, The Sir Martin Evans Building, Museum Avenue, Cardiff, CF10 3AX
The overall aim of research in my laboratory is to understand comprehensively how specific factors, such as cytokines and lipid metabolites, regulate gene expression during health and disease. In particular, we are elucidating the pathways leading from the interaction of such factors with their receptors, through the intracellular signalling cascades, to the control of gene expression in the nucleus. Specific focus is on cytokine signalling and gene expression, particularly in macrophages, in inflammatory disorders such as atherosclerosis, with the longer-term goal of identifying new therapeutic/preventative targets/avenues. Previous and current research has been funded by grants from the Wellcome Trust, BBSRC, British Heart Foundation, MRC and GlaxoSmithKline.