Dr Nicholas A. Kent - DPhil
Telephone:+44 (0)29 208 79036
Fax:+44 (0)29 208 74116
Location:School of Biosciences, The Sir Martin Evans Building, Museum Avenue, Cardiff, CF10 3AX
DNA in cells does not function as a naked double helix, but is bound by various structural proteins to form chromatin. The modulation of chromatin structure is a key process in the catalysis and regulation of gene transcription, DNA replication and DNA repair. The Kent lab uses novel next-generation chromatin sequencing techniques to analyse chromatin function in a variety of organisms including humans, plants, flies and yeast. We also hope to be a driving force in the emerging field of research into chromatin in non-nuclear genomes such as those of the archaea. The aim of our research is to understand basic chromatin biology relevant to human health, crop improvement and the evolution of genome structure. We are currently funded by the BBSRC and The Waterloo Foundation.
The Kent Lab webpages (including Supplementary Data for recent publications) can be found here