Prof Victor Duance - PhD
Telephone:+44 (0)29 208 74111
Fax:+44 (0)29 208 74594
Location:Connective Tissue Biology Laboratories, Cardiff School of Biosciences, The Sir Martin Evans Building, Museum Avenue, Cardiff, CF10 3AX
Arthritis Research UK in 2009 selected Cardiff University to become its prestigious UK Centre of Excellence in Biomechanics and Bioengineering. The Centre is driving interdisciplinary studies across a team of internationally recognised researchers and clinicians to improve patient care. The team applies a ‘molecule to man’ approach to investigate normal joint biomechanics and determine how this is influenced by pathology to inform clinical intervention and rehabilitation in musculoskeletal disorders.
There are three main themes to the work of my research group (i) the structure and function of the minor collagens of cartilage, in particular types III, IX, X and XI, how they change with age and in disease, as well as their importance in cartilage repair (ii) elucidation of the cell signalling pathways associated with mechanical and cytokine mediated cartilage degeneration and (iii) strategies for enhancing cartilage repair.